New hope for tough gut tumors: experimental drug DCC-3009 enters human trials
NCT ID NCT06630234
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called DCC-3009, alone or with other cancer treatments, for people with advanced gastrointestinal stromal tumor (GIST) that has stopped responding to standard therapy. About 120 participants will receive the drug in 28-day cycles for up to 2 years. The goal is to find safe doses and see if the drug can shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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HonorHealth
RECRUITINGScottsdate, Arizona, 85258, United States
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Mayo Clinic Florida
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
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UC San Diego Moores Cancer Center
RECRUITINGLa Jolla, California, 92093, United States
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University of Colorado Anschutz Medical Campus
RECRUITINGAurora, Colorado, 80045, United States
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University of Miami - Sylvester Comprehensive Cancer Center
RECRUITINGMiami, Florida, 33136, United States
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Vanderbilt University-Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37232, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Metabolic MRI may reveal tumor response to GIST drug in weeks, not months
- Massive GIST registry aims to unlock secrets of rare cancer
- Blood test may guide cancer care without biopsy
- New pill HQP1351 enters human testing for stubborn cancers
- New surgery aims to remove stomach tumors without major incisions
- New targeted drug takes on stomach cancer in Head-to-Head trial