Could a balloon replace stents in young heart attack patients?

NCT ID NCT07229248

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a drug-coated balloon to a standard drug-eluting stent in 496 young adults (ages 18–50) having a heart attack. The balloon delivers medication to open the artery without leaving a permanent implant, which may reduce long-term risks like blood clots and the need for extended blood thinner use. Participants will be followed for one year to see if the balloon is as safe and effective as the stent.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel-coated balloon (Prevail DCB)

What this could lead to

If successful, this could offer young heart attack patients a stent-free option that lowers the risk of future heart problems and reduces the need for long-term blood thinners.

What could go wrong

This is a single-center trial, so results may not apply everywhere. The balloon might not keep the artery open as well as a stent, and there is a small risk of the artery closing suddenly during the procedure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institute of Cardiovascular Diseases

    RECRUITING

    Karachi, Pakistan

    Contact Phone: •••-•••-•••• Email: •••••@•••••