Balloon or stent? new study aims to settle the debate for clogged arteries

NCT ID NCT06954714

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways to treat narrowed heart arteries: a drug-coated balloon (DCB) and a drug-eluting stent (DES). Researchers will measure how much the artery narrows again over time using ultrasound. About 256 adults with significant blockages will take part to see which method works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Drug-coated balloon (DCB) and drug-eluting stent (DES)
What this could lead to
If successful, this could show that balloon angioplasty is as effective as stents for keeping heart arteries open, potentially offering a stent-free option.
What could go wrong
This is a small, early-phase study (256 participants) comparing two established treatments, so it may not lead to major changes in practice. Risks include artery re-narrowing or complications from the procedure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chonnam National University

    RECRUITING

    Gwangju, Gwangju, 61469, South Korea

  • Ewha Womans University Mokdong Hospital

    NOT_YET_RECRUITING

    Seoul, Seoul, 07985, South Korea

  • Jeonbuk National University Hospital

    NOT_YET_RECRUITING

    Jeonju, Jeonju, 54907, South Korea

  • Keimyung University Dongsan Hospital

    NOT_YET_RECRUITING

    Daegu, Daegu, 42601, South Korea

  • Korea University Guro Hospital

    NOT_YET_RECRUITING

    Seoul, Seoul, 08308, South Korea

  • Kosin University Gospel Hospital

    NOT_YET_RECRUITING

    Busan, Busan, 49269, South Korea

  • Samsung Medical Center

    NOT_YET_RECRUITING

    Seoul, Seoul, 06351, South Korea

  • Ulsan University Hospital

    NOT_YET_RECRUITING

    Ulsan, Ulsan, 44033, South Korea

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