Could a sleep medication curb alcohol cravings?

NCT ID NCT07532252

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether daridorexant, a drug used for insomnia, can reduce alcohol cravings and drinking while improving sleep in people with alcohol use disorder and sleep problems. About 150 adults will receive either daridorexant or a placebo for several weeks. The goal is to see if targeting the brain's orexin system can help manage alcohol use in a real-world setting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

daridorexant

What this could lead to

If it works, this could point toward a new treatment option for alcohol use disorder that also helps with sleep problems.

What could go wrong

This is an early phase 2 trial with only 150 people, so results may not apply to everyone. The drug may not reduce drinking or craving as hoped, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••