Could a sleep medication curb alcohol cravings?
NCT ID NCT07532252
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether daridorexant, a drug used for insomnia, can reduce alcohol cravings and drinking while improving sleep in people with alcohol use disorder and sleep problems. About 150 adults will receive either daridorexant or a placebo for several weeks. The goal is to see if targeting the brain's orexin system can help manage alcohol use in a real-world setting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- daridorexant
- What this could lead to
- If it works, this could point toward a new treatment option for alcohol use disorder that also helps with sleep problems.
- What could go wrong
- This is an early phase 2 trial with only 150 people, so results may not apply to everyone. The drug may not reduce drinking or craving as hoped, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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