Blood test could spot hidden breast cancer early and guide Life-Saving treatment
NCT ID NCT04567420
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for people with a high-risk type of breast cancer (ER+/HER2-) who have finished initial treatment but still face a chance of the cancer coming back. Researchers will use a simple blood test to look for tiny bits of tumor DNA. If found, participants will be randomly assigned to get either standard hormone therapy or a stronger drug combination (palbociclib plus fulvestrant) to try to stop the cancer from returning. The goal is to see if this personalized approach improves outcomes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Locations
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Cancer Partners of Nebraska
RECRUITINGLincoln, Nebraska, 68516, United States
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Cedars-Sinai Medical Center
COMPLETEDLos Angeles, California, 90048, United States
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Intermountain
RECRUITINGGolden, Colorado, 80401, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Louisiana State University Health Sciences Center- New Orleans
RECRUITINGNew Orleans, Louisiana, 70112, United States
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New Mexico Cancer Care Alliance
RECRUITINGAlbuquerque, New Mexico, 87131, United States
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Oregon Health and Science University
RECRUITINGPortland, Oregon, 97239, United States
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PRiSMs Group
RECRUITINGLaredo, Texas, 78041, United States
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Stephenson Cancer Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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Stony Brook University Cancer Center
RECRUITINGStony Brook, New York, 11794, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Swedish Cancer Institute
RECRUITINGSeattle, Washington, 98104, United States
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The Ohio State University Wexner Medical Center James Cancer Hospital
RECRUITINGColumbus, Ohio, 43210, United States
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USC/Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Arizona Cancer Center
RECRUITINGTucson, Arizona, 85724, United States
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University of Colorado Cancer Center
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Wisconsin Clinical Science Center
RECRUITINGMadison, Wisconsin, 53792, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Virginia Cancer Institute
RECRUITINGRichmond, Virginia, 23229, United States
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Winship Cancer Institute of Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06510, United States
Contact Email: •••••@•••••
Contact