New hope for rare lymphomas: daratumumab trial targets Hard-to-Treat cancers

NCT ID NCT05907759

First seen Feb 18, 2026 · Last updated Jun 12, 2026 · Updated 20 times

Summary

This study tests a drug called daratumumab in people with three rare and aggressive blood cancers (primary effusion lymphoma, plasmablastic lymphoma, and multicentric Castleman disease) that have not responded to standard therapy. The drug is given as a weekly injection under the skin for 8 weeks, then less often, for up to 2 years. The goal is to see if it can shrink or control the cancer, with follow-up for up to 5 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.