New combo therapy aims to control multiple myeloma
NCT ID NCT04108195
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 27 times
Summary
This study tests combinations of the drug daratumumab with two other therapies (talquetamab and teclistamab) in people with multiple myeloma, a type of blood cancer. The goal is to find the safest and most effective doses and to monitor side effects. About 290 adults who have already tried at least three prior treatments will take part.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Arthur J E Child Comprehensive Cancer Centre
Calgary, Alberta, T2N 5G2, Canada
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City of Hope National Medical Center
Duarte, California, 91010, United States
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City of Hope Orange County Lennar Foundation Cancer Center
Irvine, California, 92618, United States
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Clinica Univ. de Navarra
Pamplona, 31008, Spain
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Germans Trias I Pujol
Barcelona, 08916, Spain
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Hosp Clinic de Barcelona
Barcelona, 08036, Spain
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Hosp Clinico Univ de Salamanca
Salamanca, 37007, Spain
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Hosp Univ Fund Jimenez Diaz
Madrid, 28040, Spain
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Inst. Cat. Doncologia-H Duran I Reynals
Barcelona, 08908, Spain
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LUMC
Leiden, 2333ZA, Netherlands
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Levine Cancer Institute
Charlotte, North Carolina, 28204, United States
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Medical College Of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Mount Sinai Medical Center
New York, New York, 10029, United States
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The Blavatnik Family Chelsea Medical Center at Mount Sinai
New York, New York, 10011, United States
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Universitaetsklinikum Hamburg Eppendorf
Hamburg, 20246, Germany
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Universitaetsklinikum Heidelberg
Heidelberg, 69120, Germany
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Universitatsklinikum Freiburg
Freiburg im Breisgau, 79106, Germany
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Universitatsklinikum Wurzburg
Würzburg, 97080, Germany
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University Health Network UHN Princess Margaret Cancer Centre
Toronto, Ontario, M5G 2M9, Canada
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University of California San Francisco
San Francisco, California, 94143, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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VU Medisch Centrum
Amsterdam, 1081 HV, Netherlands
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Vanderbilt Ingram Cancer Center
Nashville, Tennessee, 37232, United States
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Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, 27157, United States
Conditions
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