New combo shows promise in slowing advanced myeloma

NCT ID NCT03180736

First seen Jan 06, 2026 · Last updated May 01, 2026 · Updated 15 times

Summary

This study tested whether adding daratumumab to two standard drugs (pomalidomide and dexamethasone) could help people with multiple myeloma that came back or didn't respond to earlier treatments. 304 adults took part. The goal was to see if the triple combination could delay cancer growth longer than the two-drug regimen alone.

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Contacts and locations

Locations

  • Ancona

    Ancona, Italy

  • Anticancer Hospital of Thessaloniki "Theageneio"

    Thessaloniki, Greece

  • Antwerpen

    Antwerp, Belgium

  • Badalona

    Badalona, Spain

  • Barcelona

    Barcelona, Spain

  • Belgrade

    Belgrade, Serbia

  • Bologna

    Bologna, Italy

  • Brescia

    Brescia, Italy

  • Brno

    Brno, Czechia

  • Brussel

    Brussels, Belgium

  • Capa

    Çapa, Turkey (Türkiye)

  • Cebeci

    Cebeli, Turkey (Türkiye)

  • Doctor Peset University Hospital Medical Centre

    Valencia, Spain

  • Erasmus MC

    Rotterdam, Netherlands

  • Freiburg

    Freiburg im Breisgau, Germany

  • Gaziantep

    Gaziantep, Turkey (Türkiye)

  • General Hospital of Athens "Evangelismos"

    Athens, Greece

  • General University Hospital of Patras

    Pátrai, Greece

  • Hamburg

    Hamburg, Germany

  • Heidelberg

    Heidelberg, Germany

  • Hospital Quirón Salud Madrid

    Madrid, Spain

  • Hospital Universitario de la Princesa

    Madrid, Spain

  • Izmir

    Izmir, Turkey (Türkiye)

  • Kayseri

    Kayseri, Turkey (Türkiye)

  • Kiel

    Kiel, Germany

  • Milano

    Milan, Italy

  • Odense

    Odense, Denmark

  • Ostrava

    Ostrava, Czechia

  • Praha 2

    Prague, Czechia

  • Roma

    Roma, Italy

  • Salamanca University Hospital

    Salamanca, Spain

  • Schwerin

    Schwerin, Germany

  • Torino

    Torino, Italy

  • Tübingen

    Tübingen, Germany

  • UZ Gent

    Ghent, Belgium

  • University of Athens School of Medicine

    Athens, Greece

  • VU MC

    Amsterdam, Netherlands

  • Vejle

    Vejle, Denmark

  • Würzburg

    Würzburg, Germany

  • Yvoir

    Yvoir, Belgium

Conditions

Explore the condition pages connected to this study.