Common diabetes drug may shield hearts during chemo

NCT ID NCT06491680

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether dapagliflozin, a drug used for diabetes, can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. Forty women with breast cancer will take dapagliflozin daily alongside their chemo. Researchers will measure heart function and blood markers to see if the drug offers protection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dapagliflozin (a diabetes drug)
What this could lead to
If it works, this could offer a simple way to prevent heart damage during breast cancer chemotherapy, improving long-term heart health.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. The drug may not provide significant heart protection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Al demerdash hospital at oncology departement

    RECRUITING

    Cairo, Cairo Governorate, 202, Egypt

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