Could a common diabetes pill ease heart failure from rare protein disease?

NCT ID NCT05795400

First seen May 07, 2026 · Last updated May 07, 2026

Summary

This pilot study tested the drug dapagliflozin (a diabetes medicine) in 50 adults with heart failure due to amyloid cardiomyopathy, a condition where abnormal proteins stiffen the heart. The goal was to see if the drug improves quality of life, walking ability, and heart stress markers. Researchers measured changes in a heart failure questionnaire, a 6-minute walk test, and blood levels of NT-proBNP. The study is completed, but results are not yet reported.

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Contacts and locations

Locations

  • National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

    Moscow, 121552, Russia

Conditions

Explore the condition pages connected to this study.