New model may predict and prevent deadly transplant complication

NCT ID NCT07588945

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving the drug ruxolitinib early can prevent severe graft-versus-host disease (GvHD) in people getting a stem cell transplant. About 438 adults at intermediate-to-high risk, as identified by a special model called daGOAT, will be enrolled. The goal is to see if this approach reduces severe GvHD within the first 100 days after transplant.

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