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New combo therapy aims to wipe out leukemia in adults who Can't handle standard Kids' regimens

NCT ID NCT06738368

Recruiting now Disease control Sponsor: University of Washington Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 23 times

Summary

This study tests a chemotherapy cocktail (DA-EPOCH) plus an enzyme drug (Rylaze) in 30 adults newly diagnosed with a type of leukemia (Ph-negative ALL) who are not good candidates for the intensive regimens used in children. The goal is to see if this combination can clear cancer cells from the bone marrow more effectively. Participants will receive multiple cycles of treatment and be monitored for side effects and response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE T ACUTE LYMPHOBLASTIC LEUKEMIA