B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Clinical trials for B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE explained in plain language.
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New enzyme combo aims to improve leukemia treatment for high-risk adults
Disease control Recruiting nowThis study tests whether a new version of the drug asparaginase, made from a different bacterium, can be safely combined with standard chemotherapy for high-risk adults (ages 18–54) newly diagnosed with acute lymphoblastic leukemia or lymphoblastic lymphoma. The drug works by bre…
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 17, 2026 02:23 UTC
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New combo therapy aims to wipe out leukemia in adults who Can't handle standard Kids' regimens
Disease control Recruiting nowThis study tests a chemotherapy cocktail (DA-EPOCH) plus an enzyme drug (Rylaze) in 30 adults newly diagnosed with a type of leukemia (Ph-negative ALL) who are not good candidates for the intensive regimens used in children. The goal is to see if this combination can clear cancer…
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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New combo therapy offers hope for Hard-to-Treat leukemia
Disease control Recruiting nowThis study combines a targeted antibody-drug (inotuzumab ozogamicin) with low-intensity chemotherapy to treat acute lymphoblastic leukemia (ALL). It includes older adults (60+) with newly diagnosed ALL and younger adults (18-59) who are not fit for standard chemo, as well as pati…
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 06, 2026 16:13 UTC
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New Two-Pronged attack tested for tough blood cancer in older adults
Disease control Recruiting nowThis study is testing a combination of two targeted drugs, inotuzumab ozogamicin and blinatumomab, for adults with a specific type of acute lymphoblastic leukemia (ALL). It is for older adults newly diagnosed with this cancer or adults whose cancer has come back or hasn't respond…
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 07, 2026 14:36 UTC