Gene therapy mends wounds in rare 'butterfly skin' disease
NCT ID NCT06892639
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a treatment called D-Fi, made from a person's own skin cells that are genetically modified to produce a missing protein. It aims to see if injecting these cells into wounds helps them close completely compared to standard care alone. The trial includes 32 children and adults with dystrophic epidermolysis bullosa, a condition that causes fragile skin and chronic wounds.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Mission Dermatology
Santa Margarita, California, 92688, United States
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Stanford University School of Medicine, Dermatology
Redwood City, California, 94063, United States
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University of Massachusetts
Worcester, Massachusetts, 01655, United States