New PET/MRI scan could spot elusive brain tumors in Cushing's patients
NCT ID NCT03346954
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a special scan called [11C]-Methionine PET/MRI can better locate tiny pituitary tumors that cause Cushing's disease. Standard MRI often misses these tumors, leading to risky exploratory surgery. The study involved 33 adults with confirmed Cushing's disease who received the new scan before surgery. If successful, this approach could reduce the need for invasive catheter tests and improve surgical outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- [11C]-Methionine (a radioactive tracer used in PET imaging)
- What this could lead to
- If this scan works well, it could help doctors find hidden pituitary tumors more accurately, reducing the need for invasive catheter tests and improving surgical success.
- What could go wrong
- This was a small, completed study with only 33 people, so results may not apply to everyone. The scan may still miss some tumors or give false positives.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Service de Médecine Nucléaire - Hospices Civils de Lyon
Bron, 69677, France
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Other studies related to the condition(s) this trial covers.
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- Cushing's patients wanted for Long-Term health tracking study
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