Turmeric and black pepper combo tested to fight inflammation after heart attack

NCT ID NCT07149961

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study tested whether a supplement combining curcumin (from turmeric) and piperine (from black pepper) can reduce inflammation and oxidative stress in 50 adults who had a heart attack and underwent a procedure to open blocked arteries. Participants took the supplement or a placebo for 28 days. Researchers measured blood markers of inflammation and oxidative stress at the start, shortly after the procedure, and after 28 days to see if the supplement offered extra protection.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
curcumin and piperine (turmeric and black pepper extract)
What this could lead to
If it works, this could point toward a simple, natural supplement to help reduce inflammation and oxidative stress after a heart attack, potentially improving recovery.
What could go wrong
This is a small, completed trial with only 50 participants, so results may not apply widely. The supplement may not show significant benefits over standard care, and high doses could affect liver or kidney function.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Universitas Diponegoro

    Semarang, Central Java, 50275, Indonesia

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