Turmeric power: could curcumin nanogels replace steroids for a painful mouth condition?

NCT ID NCT06932848

Recruiting now Disease control Sponsor: Chulalongkorn University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares curcumin nanogels (a natural turmeric extract) to a standard steroid paste for treating atrophic-erosive oral lichen planus, a chronic inflammatory mouth condition. Thirty adults will apply either treatment three times daily for four weeks. Researchers will measure changes in disease activity and patient satisfaction, hoping to find a gentler, effective option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: curcumin in nanogels
What this could lead to: If it works, this could offer a natural, better-tolerated alternative to steroid treatment for managing oral lichen planus symptoms.
What could go wrong: This is a small, early-stage trial with only 30 participants. Curcumin may prove less effective than the standard steroid, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autoimmune disease lichen planus, oral oral erosive lichen

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL LICHEN PLANUS

Contacts and locations

Locations

Faculty of Dentistry, Chulalongkorn University
RECRUITING

Bangkok, 10400, Thailand

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