New drug targets Hard-to-Treat cancers in early trial

NCT ID NCT05360680

First seen Jan 23, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This early-stage study tested a new drug called CUE-102 in 42 adults with certain advanced cancers (colorectal, stomach, pancreatic, or ovarian) that had returned or spread and were no longer responding to standard treatments. The goal was to find a safe dose and see if the drug could shrink tumors. Participants received the drug by IV, and researchers monitored side effects and tumor changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

  • Carol G. Simon Cancer Center - Morristown Medical Center

    Morristown, New Jersey, 07960, United States

  • Carolina BioOncology Institute

    Huntersville, North Carolina, 28078, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Cleveland Medical Center (University Hospitals)

    Cleveland, Ohio, 44106, United States

  • Gabrail Cancer Center

    Canton, Ohio, 44718, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21231, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic - Rochester

    Rochester, Minnesota, 55905, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • Northwest Medical Specialties, PLLC

    Tacoma, Washington, 98405, United States

  • Stanford Advanced Medicine Cancer Center

    Palo Alto, California, 94304, United States

  • Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.