Engineered cells take aim at tough autoimmune diseases
NCT ID NCT06925542
First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 22 times
Summary
This early-stage study tests a new treatment called CTX112 for people with severe autoimmune diseases like lupus, scleroderma, or myositis that haven't improved with standard therapies. CTX112 uses specially engineered immune cells from a donor to target and attack faulty immune cells causing the disease. The main goal is to check safety, but researchers will also look for signs that the treatment is working.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site 1
RECRUITINGSt Louis, Missouri, 63130, United States
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Research Site 2
RECRUITINGChicago, Illinois, 63110, United States
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Research Site 3
RECRUITINGHanover, 30625, Germany
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Research Site 4
RECRUITINGRedwood City, California, 94063, United States
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Research Site 5
RECRUITINGChapel Hill, North Carolina, 27599, United States
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Research Site 6
RECRUITINGBoston, Massachusetts, 02118, United States
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Research Site 7
NOT_YET_RECRUITINGAugsburg, 86156, Germany
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Research Site 8
RECRUITINGIowa City, Iowa, 52242, United States
Conditions
Explore the condition pages connected to this study.