New study seeks to uncover hidden cancer risks in families with rare gene mutation

NCT ID NCT05126290

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at people with a specific genetic change in the CTNNA1 gene, which may increase the risk of stomach and breast cancers. Researchers will collect family health histories from 100 participants to better understand these risks. The goal is to improve cancer screening and prevention for families carrying this gene variant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could clarify the cancer risks associated with CTNNA1 mutations, helping guide screening and prevention for affected families.

What could go wrong

This is an observational study, not a treatment trial. It may not find clear links due to small sample size or genetic complexity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm gastric cancer gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact