Simple blood test could spot hidden germ cell cancer

NCT ID NCT07401316

Recruiting now Diagnosis Sponsor: Indiana University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a blood test that looks for tumor DNA can find leftover cancer cells in people with germ cell tumors (a type of testicular or ovarian cancer). Researchers will enroll 130 patients with stage I, II, or III disease and check how well the test works after treatment. The goal is to develop a tool to detect cancer early and improve follow-up care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blood test for circulating tumor DNA (ctDNA)
What this could lead to: If successful, this blood test could help doctors find leftover cancer cells after treatment, potentially guiding further care.
What could go wrong: This is an early-stage study with only 130 participants, so results may not apply to all patients. The test may not be accurate enough for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

germ cell tumor malignant germ cell tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GERM CELL CANCER METASTATIC

Contacts and locations

Locations

Indiana University Melvin and Bren Simon Comprehensive Cancer Center
RECRUITING

Indianapolis, Indiana, 46202, United States

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