Blood test could revolutionize rectal cancer monitoring

NCT ID NCT05629442

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study looks at whether a blood test that finds tiny bits of tumor DNA (ctDNA) can help doctors monitor rectal cancer more closely than standard scans. Researchers will collect blood and tissue samples from 60 adults with non-spreading rectal cancer before and after standard treatments. The goal is to see if ctDNA can predict if the cancer is completely gone or if it comes back, potentially allowing some patients to avoid surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mass General Cancer Center Newton-Wellesley Hospital

    Newton, Massachusetts, 02462, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

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