Blood test may spare some women from radiation after endometrial cancer surgery

NCT ID NCT07339384

First seen Jan 14, 2026 · Last updated Apr 30, 2026 · Updated 10 times

Summary

This study looks at whether a blood test that detects tumor DNA (ctDNA) can help decide if women with early-stage endometrial cancer need radiation after surgery. About 1,010 women will be followed for 3 years. Those with no ctDNA in their blood may skip radiation and be monitored instead, with the goal of seeing if their cancer returns at the same low rate as those who received radiation.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health Levine Cancer

    Charlotte, North Carolina, 28204, United States

    Contact

  • Cleveland Clinic

    Cleveland, Ohio, 44106, United States

    Contact

  • Duke University

    Durham, North Carolina, 27708, United States

    Contact

  • New York University

    New York, New York, 10016, United States

    Contact

  • Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States

    Contact

  • University of Alabama at Birmingham Hospital

    Birmingham, Alabama, 35294, United States

    Contact

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

    Contact

  • University of California, San Diego

    La Jolla, California, 92093, United States

    Contact

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

    Contact

Conditions

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