Blood test may personalize esophageal cancer therapy

NCT ID NCT06792786

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether monitoring tumor DNA in the blood (ctDNA) can help guide treatment for esophageal cancer. Researchers will give patients immunotherapy and chemotherapy, followed by chemoradiotherapy, and track ctDNA levels to see if they predict outcomes. The goal is to improve survival for people with advanced esophageal cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Toripalimab, paclitaxel, cisplatin

What this could lead to

If successful, this approach could lead to more personalized and effective treatment for esophageal cancer, potentially improving survival rates.

What could go wrong

This is a small, early-phase study with only 30 participants, so results may not apply to everyone. The treatment involves chemotherapy and immunotherapy, which can cause significant side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ESOPHAGEAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms esophageal squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Jinhua Municipal Central Hospital

    RECRUITING

    Jinhua, Zhejiang, 321000, China

  • The central Hospital of Lishui City

    RECRUITING

    Lishui, Zhejiang, 323000, China