Spinal fluid test may spot brain damage early after hemorrhage

NCT ID NCT04998370

Completed Knowledge-focused Sponsor: University of Zurich Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 366 people who had a brain bleed from a burst aneurysm. Researchers measured hemoglobin in the fluid around the brain and spine to see if it could predict secondary brain injury, like artery spasms or lack of blood flow. The goal is to find a better way to monitor patients and catch complications early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple test to catch brain complications early after a brain bleed.
What could go wrong: This is an observational study, not a treatment trial. It only measures a marker, so it won't directly improve outcomes. Results may not change current care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acquired aneurysmal subarachnoid hemorrhage brain ischemia intracranial vasospasm subarachnoid hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DELAYED CEREBRAL ISCHEMIA DELAYED ISCHEMIC NEUROLOGICAL DEFICIT SUBARACHNOID HEMORRHAGE, ANEURYSMAL VASOSPASM

Contacts and locations

Locations

Johannes Kepler Universität Linz, Universitätsklinik für Neurochirurgie

Linz, 4040, Austria
Kantonsspital Aarau

Aarau, Canton of Aargau, CH-5001, Switzerland
Kantonsspital St. Gallen

Sankt Gallen, Canton of St. Gallen, CH-9007, Switzerland
Klinikum rechts der Isar TUM

München, Bavaria, 81675, Germany
Medizinische Universität Wien, Klinik für Neurochirurgie

Vienna, 1090, Austria
University Hospital Zurich

Zurich, Canton of Zurich, 8091, Switzerland
Universitätsklinikum Mannheim

Mannheim, Baden-Wurttemberg, 68167, Germany
Universitätsklinikum Tübingen

Tübingen, Tübingen, 72076, Germany

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