New hope against a 100% fatal brain infection: massive trial launches

NCT ID NCT06666322

First seen Jan 10, 2026 · Last updated May 14, 2026 · Updated 18 times

Summary

This study tests new drug combinations for cryptococcal meningitis, a brain infection that is always fatal without treatment and still kills many people with HIV. The trial aims to find safer, more effective therapies that are easier to access worldwide. About 2,000 adults with HIV and this infection will join to compare how well different treatments clear the infection and improve survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Infectious Diseases Institute

    RECRUITING

    Kampala, Uganda

    Contact Email: •••••@•••••

  • Mbarara University of Science and Technology

    RECRUITING

    Mbarara, Uganda

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.