New mRNA vaccine aims to stop ovarian Cancer's return

NCT ID NCT07665515

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This early-stage trial tests a new mRNA cancer vaccine called CryptiVax-1001 in 50 women with advanced ovarian cancer. The vaccine is designed to train the immune system to recognize and attack cancer cells, potentially delaying or preventing the cancer from coming back. The main goal is to check safety and side effects, but researchers will also look at how well the vaccine activates the immune system.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CryptiVax-1001 (mRNA cancer vaccine)

What this could lead to

If it works, this vaccine could help delay or prevent ovarian cancer from returning after standard treatment.

What could go wrong

This is an early phase 1 trial with only 50 people, so it is too soon to know if it works. The main goal is safety, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

fallopian tube serous adenocarcinoma ovarian cancer ovarian serous adenocarcinoma primary peritoneal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beatson West of Scotland Cancer Centre

    NOT_YET_RECRUITING

    Glasgow, G12 0YN, United Kingdom

  • Cambridge University Hospitals NHS Foundation Trust - Addenbrookes Hospital

    NOT_YET_RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

  • Guy's and St Thomas' NHS Foundation Trust - Guy's Hospital

    NOT_YET_RECRUITING

    London, SE1 9RT, United Kingdom

  • Lancashire Teaching Hospitals NHS Foundation Trust - Royal Preston Hospital

    NOT_YET_RECRUITING

    Preston, PR2 9HT, United Kingdom

  • Royal Marsden NHS Foundation Trust - Institute of Cancer Research

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

  • Royal Marsden NHS Foundation Trust - Royal Marsden Hospital

    RECRUITING

    London, SW3 6JJ, United Kingdom

  • St. James's University Hospital

    NOT_YET_RECRUITING

    Leeds, LS9 7TF, United Kingdom

  • The University of Edinburgh - Western General Hospital - Edinburgh Cancer Research Centre

    NOT_YET_RECRUITING

    Edinburgh, EH4 2XR, United Kingdom

  • University College London Hospitals NHS Foundation Trust - Cancer Clinical Trials Unit

    RECRUITING

    London, NW1 2PG, United Kingdom

  • University Hospitals of Leicester NHS Trust -Leicester Royal Infirmary

    RECRUITING

    Leicester, LE2 7LX, United Kingdom