New mRNA vaccine aims to stop ovarian Cancer's return

NCT ID NCT07665515

Recruiting now Disease control Sponsor: Epitopea Ltd Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 8 times

Summary

This early-stage trial tests a new mRNA cancer vaccine called CryptiVax-1001 in 50 women with advanced ovarian cancer. The vaccine is designed to train the immune system to recognize and attack cancer cells, potentially delaying or preventing the cancer from coming back. The main goal is to check safety and side effects, but researchers will also look at how well the vaccine activates the immune system.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CryptiVax-1001 (mRNA cancer vaccine)
What this could lead to: If it works, this vaccine could help delay or prevent ovarian cancer from returning after standard treatment.
What could go wrong: This is an early phase 1 trial with only 50 people, so it is too soon to know if it works. The main goal is safety, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

fallopian tube serous adenocarcinoma ovarian cancer ovarian serous adenocarcinoma primary peritoneal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HGS OVARIAN, FALLOPIAN TUBE OR PRIMARY PERITONEAL CANCER HGSOC OVARIAN CANCER

Contacts and locations

Locations

Beatson West of Scotland Cancer Centre
RECRUITING

Glasgow, G12 0YN, United Kingdom
Cambridge University Hospitals NHS Foundation Trust - Addenbrookes Hospital
RECRUITING

Cambridge, CB2 0QQ, United Kingdom
Guy's and St Thomas' NHS Foundation Trust - Guy's Hospital
NOT_YET_RECRUITING

London, SE1 9RT, United Kingdom
Lancashire Teaching Hospitals NHS Foundation Trust - Royal Preston Hospital
NOT_YET_RECRUITING

Preston, PR2 9HT, United Kingdom
Royal Marsden NHS Foundation Trust - Institute of Cancer Research
RECRUITING

Sutton, SM2 5PT, United Kingdom
Royal Marsden NHS Foundation Trust - Royal Marsden Hospital
RECRUITING

London, SW3 6JJ, United Kingdom
St. James's University Hospital
RECRUITING

Leeds, LS9 7TF, United Kingdom
The University of Edinburgh - Western General Hospital - Edinburgh Cancer Research Centre
NOT_YET_RECRUITING

Edinburgh, EH4 2XR, United Kingdom
University College London Hospitals NHS Foundation Trust - Cancer Clinical Trials Unit
RECRUITING

London, NW1 2PG, United Kingdom
University Hospitals of Leicester NHS Trust -Leicester Royal Infirmary
RECRUITING

Leicester, LE2 7LX, United Kingdom

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