Ice vs spray: which stops chemo mouth pain?
NCT ID NCT07727031
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial compares two simple treatments—sucking on ice chips or using a lidocaine spray—to see which better prevents or reduces painful mouth sores caused by chemotherapy. About 60 adults with cancer who are about to receive chemotherapy will be randomly assigned to one of the two approaches. Researchers will track sore severity and pain levels to find out which method offers more relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- oral cryotherapy (ice chips) and topical lidocaine spray
- What this could lead to
- If one method works better, it could offer a simple, low-cost way to prevent or ease painful mouth sores during chemotherapy.
- What could go wrong
- This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. Both methods may provide only partial relief.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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