Freezing foot pain: new study tests cryoablation for Morton's neuroma
NCT ID NCT05501262
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
Morton's neuroma causes burning or shooting pain in the ball of the foot, often in middle-aged women. This study compares freezing the nerve (cryoablation) plus a steroid/lidocaine injection against the injection alone. 32 adults who haven't improved with orthotics or pads will be followed for pain, function, and quality of life over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cryoablation (freezing) using the ICE-Seed needle plus steroid and lidocaine injection
- What this could lead to
- If successful, this could offer a more effective, less invasive option for Morton's neuroma pain that hasn't improved with conservative care.
- What could go wrong
- This is a small early-stage study (32 people) comparing two treatments, so results may not apply widely. Cryoablation carries risks like numbness or nerve damage, and the benefit over steroid alone is not yet proven.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Oregon Health Sciences University
RECRUITINGPortland, Oregon, 97239, United States
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