Freezing foot pain: new study tests cryoablation for Morton's neuroma
NCT ID NCT05501262
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
Morton's neuroma causes burning or shooting pain in the ball of the foot, often in middle-aged women. This study compares freezing the nerve (cryoablation) plus a steroid/lidocaine injection against the injection alone. 32 adults who haven't improved with orthotics or pads will be followed for pain, function, and quality of life over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cryoablation (freezing) using the ICE-Seed needle plus steroid and lidocaine injection
What this could lead to
If successful, this could offer a more effective, less invasive option for Morton's neuroma pain that hasn't improved with conservative care.
What could go wrong
This is a small early-stage study (32 people) comparing two treatments, so results may not apply widely. Cryoablation carries risks like numbness or nerve damage, and the benefit over steroid alone is not yet proven.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Oregon Health Sciences University
RECRUITINGPortland, Oregon, 97239, United States
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