Freezing heart troubles: new device aims to stop ventricular tachycardia

NCT ID NCT07650032

Recruiting now Disease control Sponsor: Adagio Medical Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

This study tests a new device that uses extreme cold to destroy small areas of heart tissue causing a dangerous fast heartbeat called ventricular tachycardia. The trial will include 100 adults with this condition who have not responded to medication. Researchers will check if the procedure is safe and effectively prevents the abnormal rhythm for at least 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cryoablation device (vCLAS Ventricular Ablation System)
What this could lead to: If successful, this could provide a new, safer way to control dangerous heart rhythms without needing lifelong medication.
What could go wrong: This is an early-stage study with only 100 people. The procedure carries risks like heart damage or bleeding, and it may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VENTRICULAR TACHYCARDIA, MONOMORPHIC VENTRICULAR TACHYCARDIA, SUSTAINED

Contacts and locations

Locations

Banner University Medical Center Phoenix
RECRUITING

Phoenix, Arizona, 85006, United States
Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Hospital of University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
McGill University Health Centre (MUHC), Montreal General Hospital (MGH)
RECRUITING

Montreal, Quebec, H3G 1A4, Canada
Medical Center of South Carolina (MUSC)
RECRUITING

Charleston, South Carolina, 29403, United States
MemorialCare Long Beach Medical Center
RECRUITING

Long Beach, California, 90806, United States
Montreal Hear Institute
RECRUITING

Montreal, Canada
Northwell Health- Staten Island University Hospital
RECRUITING

Staten Island, New York, 10305, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
Virginia Commonwealth University
RECRUITING

Richmond, Virginia, 23219, United States

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