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A simple blood test could curb antibiotic overuse in indonesia

NCT ID NCT07717372

Disease control Sponsor: Oxford University Clinical Research Unit Indonesia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This trial investigates whether a rapid C-reactive protein (CRP) blood test can help doctors decide when antibiotics are truly needed for adults with acute respiratory infections in Indonesian primary health clinics. Many such infections are viral and do not require antibiotics, yet overprescribing is common and fuels antimicrobial resistance. The study compares usual care with care supported by CRP test results, aiming to reduce unnecessary antibiotic prescriptions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
C-reactive protein point-of-care testing (CRP POCT) using the ACTIM CRP test
What this could lead to
If effective, this approach could reduce unnecessary antibiotic use, helping to slow antimicrobial resistance and lower healthcare costs in Indonesia.
What could go wrong
The test may not change prescribing habits as expected, or results may not apply to other settings. The trial is also limited to adults with mild infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 2,544 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults aged ≥18 years. 2. Presenting to the PHC site for the first consultation of the current episode of Acute-Respiratory Tract Infections (ARTI). 3. Reporting at least one of the following symptoms or clinical signs within the past 5 days: cough, rhinitis (e.g., sneezing, nasal congestion, or runny nose), pharyngitis (e.g., sore throat), shortness of breath, wheezing, chest pain, abnormal lung sounds on auscultation. Exclusion Criteria: 1. Presenting with severe illness requiring referral to a higher-level healthcare facility (e.g., hospital). 2. Having known immunosuppression or chronic conditions, including but not limited to: HIV infection; chronic liver disease; history of malignancy; long-term use of systemic corticosteroids or other immunosuppressive therapies, as assessed by the healthcare worker or study team. 3. Having taken antibiotics prior to the visit to the primary health center.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute respiratory tract infection Adults Antibiotic prescriptions

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    8 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Cakung Public Health Center

    RECRUITING

    Jakarta, 13930, Indonesia

  • Cengkareng Public Health Center

    RECRUITING

    Jakarta, 11730, Indonesia

  • Cilincing Public Health Center

    RECRUITING

    Jakarta, 14120, Indonesia

  • Duren Sawit Public Health Center

    RECRUITING

    Jakarta, 13440, Indonesia

  • Jatinegara Public Health Center

    RECRUITING

    Jakarta, 13310, Indonesia

  • Kebayoran Lama Public Health Center

    ENROLLING_BY_INVITATION

    Jakarta, 12240, Indonesia

  • Koja Public Health Center

    RECRUITING

    Jakarta, 14260, Indonesia

  • Pulo Gadung Public Health Center

    RECRUITING

    Jakarta, 13220, Indonesia

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