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Crohn's treatment dilemma: switch drugs or increase dose?

NCT ID NCT06180382

Recruiting now Disease control Sponsor: Centre Hospitalier Universitaire de Saint Etienne Source: ClinicalTrials.gov ↗

Summary

This study aims to find the best next step for Crohn's disease patients whose current medication (adalimumab) stops working effectively, even though drug levels in their blood remain adequate. Researchers will compare two approaches: switching to a different type of medication (vedolizumab) versus increasing the dose of the current medication. The goal is to see which strategy helps more patients achieve remission, reduce symptoms, and heal intestinal inflammation over 24 weeks.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHM

    RECRUITING

    Marseille, 13000, France

    Contact

    Contact

  • APHP - Hôpital Bicêtre

    RECRUITING

    Le Kremlin-Bicêtre, Paris, 94270, France

    Contact

    Contact

  • Assistance Publique - Hôpitaux de Paris

    RECRUITING

    Paris, 75004, France

    Contact

    Contact

  • CHRU Lille

    RECRUITING

    Lille, 59037, France

    Contact

    Contact

  • CHU Amiens

    RECRUITING

    Amiens, 80000, France

    Contact

    Contact

  • CHU Bordeaux

    RECRUITING

    Pessac, 33604, France

    Contact

    Contact

  • CHU Montpellier

    RECRUITING

    Montpellier, 34295, France

    Contact

    Contact

  • CHU Rennes

    RECRUITING

    Rennes, 35033, France

    Contact

    Contact

  • CHU de Saint-Etienne

    RECRUITING

    Saint-Etienne, 42055, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Ch Lyon Sud

    RECRUITING

    Pierre-Bénite, 69230, France

    Contact

    Contact

  • Chu Limoges

    RECRUITING

    Limoges, 87000, France

    Contact

    Contact

  • Hôpital de l'Archet II

    RECRUITING

    Nice, 06202, France

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.

CROHN'S DISEASE