New hope for kids with severe Crohn's disease
NCT ID NCT06332534
Summary
This study is testing whether an oral medication called upadacitinib can help control Crohn's disease in children aged 2 to 18 who haven't responded well to standard treatments. About 110 children worldwide will take the medication daily for up to 3 years while doctors monitor their symptoms and check for side effects. The goal is to reduce inflammation in the digestive tract and help children achieve remission from this chronic condition.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Addenbrookes Hospital /ID# 262707
RECRUITINGCambridge, Cambridgeshire, CB2 2QQ, United Kingdom
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Agia Sofia Hospital /ID# 261792
RECRUITINGAthens, Attica, 11527, Greece
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Azienda Ospedaliera Universitaria Gaetano Martino /ID# 262380
RECRUITINGMessina, 98125, Italy
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Beijing Children's Hospital /ID# 262258
RECRUITINGBeijing, Beijing Municipality, 100045, China
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Boston Children's Hospital /ID# 262191
RECRUITINGBoston, Massachusetts, 02115, United States
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CHR de la Citadelle /ID# 261749
RECRUITINGLiège, 4000, Belgium
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CHU de CAEN - Hopital de la Cote de Nacre /ID# 262311
RECRUITINGCaen, Calvados, 14033, France
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Children's Hospital Colorado - Aurora /ID# 262207
RECRUITINGAurora, Colorado, 80045, United States
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Children's Hospital at Westmead /ID# 262350
RECRUITINGWestmead, New South Wales, 2145, Australia
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Children's Hospital of Philadelphia - Main /ID# 262197
RECRUITINGPhiladelphia, Pennsylvania, 19104-4319, United States
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Children's Hospital of Shanghai /ID# 262356
RECRUITINGShanghai, Shanghai Municipality, 200062, China
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Christchurch Hospital. /ID# 262577
RECRUITINGChristchurch, Canterbury, 8011, New Zealand
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Clinical Research Investigator Group, LLC /ID# 262357
RECRUITINGBayamón, 00960, Puerto Rico
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Clinical Research Puerto Rico /ID# 279595
RECRUITINGSan Juan, 00909-1711, Puerto Rico
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Cliniques Universitaires UCL Saint-Luc /ID# 261741
RECRUITINGBrussels, Brussels Capital, 1200, Belgium
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Connecticut Children's Medical Center - Hartford /ID# 262256
RECRUITINGHartford, Connecticut, 06106, United States
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Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 262811
RECRUITINGLondon, Greater London, E1 2ES, United Kingdom
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico /ID# 275276
RECRUITINGMilan, 20122, Italy
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Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 262384
RECRUITINGSan Giovanni Rotondo, Foggia, 71013, Italy
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Galileo Medical Research Ltda /ID# 262602
RECRUITINGJuiz de Fora, Minas Gerais, 36033-318, Brazil
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Gastromed Sp. z o.o /ID# 262367
RECRUITINGTorun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland
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General Hospital of Chest Diseases of Athens SOTIRIA /ID# 261790
RECRUITINGAthens, Attica, 11527, Greece
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Guangzhou Medical University Affiliated Women and Children's Medical Center /ID# 262596
RECRUITINGGuangzhou, Guangdong, 510620, China
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Henan Children's Hospital Zhengzhou Children's Hospital /ID# 262300
RECRUITINGZhengzhou, Henan, 450018, China
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Hopitaux de Paris (AP-HP) - Hopital Robert Debre - CHU /ID# 262308
RECRUITINGParis, 75019, France
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Hospices Civils de Lyon - Hôpital Femme Mère Enfant /ID# 263422
RECRUITINGBron, Rhone, 69500, France
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Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 262226
RECRUITINGFerrol, A Coruna, 15405, Spain
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Hospital Clinico Universitario Lozano Blesa /ID# 262227
COMPLETEDZaragoza, 50009, Spain
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Hospital Pequeno Príncipe /ID# 262600
RECRUITINGCuritiba, Paraná, 80250-060, Brazil
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Hospital Regional Universitario de Malaga /ID# 262228
RECRUITINGMálaga, 29011, Spain
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Hospital Sant Joan de Deu /ID# 262599
RECRUITINGEsplugues de Llobregat, Barcelona, 08950, Spain
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Hospital Sirio Libanes /ID# 262670
RECRUITINGSão Paulo, 01308-050, Brazil
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Hospital Universitario Virgen del Rocio /ID# 262712
RECRUITINGSeville, 41013, Spain
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Hospital Universite Enfants Reine Fabiola /ID# 261744
RECRUITINGBrussels, 1020, Belgium
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Hunan Children's Hospital /ID# 262512
RECRUITINGChangsha, Hunan, 410007, China
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IWK Health Center /ID# 262543
RECRUITINGHalifax, Nova Scotia, B3K 6R8, Canada
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Icahn School of Medicine at Mount Sinai /ID# 262216
RECRUITINGNew York, New York, 10029, United States
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Indiana University Health Riley Hospital for Children /ID# 262215
RECRUITINGIndianapolis, Indiana, 46202, United States
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Institute of Science Tokyo Hospital /ID# 262510
RECRUITINGBunkyo-ku, Tokyo, 113-8519, Japan
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Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 262366
RECRUITINGWarsaw, Masovian Voivodeship, 04-730, Poland
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Irmandade da Santa Casa de Misericordia de Porto Alegre /ID# 262601
RECRUITINGPorto Alegre, Rio Grande do Sul, 90020-090, Brazil
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Jiangxi Provincial Children's Hospital /ID# 262295
RECRUITINGNanchang, Jiangxi, 330006, China
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Kurume University Hospital /ID# 262455
RECRUITINGKurume-shi, Fukuoka, 830-0011, Japan
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Linkou Chang Gung Memorial Hospital /ID# 261696
RECRUITINGTaoyuan, 333, Taiwan
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Lucile Packard Children's Hospital /ID# 262193
RECRUITINGPalo Alto, California, 94304, United States
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MNGI Digestive Health, P. A. /ID# 262204
RECRUITINGMinneapolis, Minnesota, 55413-2195, United States
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Miyagi Children's Hospital /ID# 262459
RECRUITINGSendai, Miyagi, 989-3126, Japan
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Monash Health - Monash Medical Centre /ID# 262878
RECRUITINGClayton, Victoria, 3168, Australia
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National Center For Child Health And Development /ID# 262456
RECRUITINGSetagaya City, Tokyo, 157-8535, Japan
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National Taiwan University Hospital /ID# 261695
RECRUITINGTaipei City, Taipei, 100, Taiwan
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Norfolk and Norwich University Hospitals NHS Foundation Trust /ID# 262778
RECRUITINGNorwich, Norfolk, NR4 7UY, United Kingdom
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OSF St. Francis Medical Center /ID# 262192
RECRUITINGPeoria, Illinois, 61637-0001, United States
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Osaka Women's and Children's Hospital /ID# 262549
RECRUITINGIzumi-Shi, Osaka, 594-1101, Japan
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Ospedale Pediatrico Bambino Gesù /ID# 262379
RECRUITINGRome, Roma, 00165, Italy
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Perth Children'S Hospital /ID# 272905
RECRUITINGPerth, Western Australia, 6009, Australia
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Puerto Rico Health Institute /ID# 262358
RECRUITINGDorado, 00646, Puerto Rico
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Queensland Children's Hospital /ID# 262351
RECRUITINGSouth Brisbane, Queensland, 4101, Australia
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Rocco & Nazato Servicos Medicos /ID# 262485
RECRUITINGSão Paulo, São Paulo, 04543-011, Brazil
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Royal Hospital for Children and Young People /ID# 262388
RECRUITINGEdinburgh, EH16 4TJ, United Kingdom
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Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 262502
RECRUITINGShanghai, Shanghai Municipality, 200065, China
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Saga University Hospital /ID# 262753
RECRUITINGSaga, Saga-ken, 849-8501, Japan
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Saitama Children's Medical Center /ID# 262461
RECRUITINGSaitama-shi, Saitama, 330-8777, Japan
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Samsung Medical Center /ID# 262323
RECRUITINGSeoul, Seoul Teugbyeolsi, 06351, South Korea
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Seoul National University Hospital /ID# 262324
RECRUITINGSeoul, Seoul Teugbyeolsi, 03080, South Korea
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Sheffield Children's Hospital NHS Foundation Trust /ID# 261832
RECRUITINGSheffield, England, S10 2TH, United Kingdom
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Shengjing Hospital of China Medical University /ID# 262301
RECRUITINGShenyang, Liaoning, 110022, China
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Specialized Hospital For Active Treatment Of Children Diseases Prof. Ivan Mitev /ID# 262589
RECRUITINGSofia, 1606, Bulgaria
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Starship Child Health /ID# 262576
COMPLETEDAuckland, 0629, New Zealand
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Sydney Children's Hospital /ID# 262352
RECRUITINGRandwick, New South Wales, 2031, Australia
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The Children's Hospital of Zhejiang University School of Medicine /ID# 262337
RECRUITINGHangzhou, Zhejiang, 310003, China
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The Sixth Affiliated Hospital of Sun Yat-sen University /ID# 272807
RECRUITINGGuangzhou, Guangdong, 510655, China
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Tokyo Metropolitan Children's Medical Center /ID# 262550
RECRUITINGFuchu-shi, Tokyo, 183-8561, Japan
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Toyama Prefectural Central Hospital /ID# 262739
RECRUITINGToyama, Toyama, 930-8550, Japan
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Tsujinaka Hospital - Kashiwanoha /ID# 262454
RECRUITINGKashiwa-shi, Chiba, 277-0871, Japan
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UCL Namur University Hospital, Site Sainte-Elisabeth /ID# 261750
RECRUITINGNamur, 5000, Belgium
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UCSF Benioff Children's Hospital - Oakland /ID# 262217
RECRUITINGOakland, California, 94609, United States
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UH Cleveland Medical Center /ID# 262188
RECRUITINGCleveland, Ohio, 44106, United States
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UMHAT Sveti Georgi /ID# 262590
RECRUITINGPlovdiv, 4002, Bulgaria
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Univ NC Chapel Hill /ID# 262198
RECRUITINGChapel Hill, North Carolina, 27514-4220, United States
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Universitair Ziekenhuis Leuven /ID# 261740
RECRUITINGLeuven, Vlaams-Brabant, 3000, Belgium
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University General Hospital of Heraklion PA.G.N.I /ID# 261791
RECRUITINGHeraklion, Crete, 71500, Greece
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Uza /Id# 261745
RECRUITINGEdegem, Antwerpen, 2650, Belgium
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Yonsei University Health System Severance Hospital /ID# 262721
RECRUITINGSeoul, Seoul Teugbyeolsi, 03722, South Korea
Conditions
Explore the condition pages connected to this study.