New hope for kids with severe Crohn's disease

NCT ID NCT06332534

Summary

This study is testing whether an oral medication called upadacitinib can help control Crohn's disease in children aged 2 to 18 who haven't responded well to standard treatments. About 110 children worldwide will take the medication daily for up to 3 years while doctors monitor their symptoms and check for side effects. The goal is to reduce inflammation in the digestive tract and help children achieve remission from this chronic condition.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrookes Hospital /ID# 262707

    RECRUITING

    Cambridge, Cambridgeshire, CB2 2QQ, United Kingdom

  • Agia Sofia Hospital /ID# 261792

    RECRUITING

    Athens, Attica, 11527, Greece

  • Azienda Ospedaliera Universitaria Gaetano Martino /ID# 262380

    RECRUITING

    Messina, 98125, Italy

  • Beijing Children's Hospital /ID# 262258

    RECRUITING

    Beijing, Beijing Municipality, 100045, China

  • Boston Children's Hospital /ID# 262191

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • CHR de la Citadelle /ID# 261749

    RECRUITING

    Liège, 4000, Belgium

  • CHU de CAEN - Hopital de la Cote de Nacre /ID# 262311

    RECRUITING

    Caen, Calvados, 14033, France

  • Children's Hospital Colorado - Aurora /ID# 262207

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Children's Hospital at Westmead /ID# 262350

    RECRUITING

    Westmead, New South Wales, 2145, Australia

  • Children's Hospital of Philadelphia - Main /ID# 262197

    RECRUITING

    Philadelphia, Pennsylvania, 19104-4319, United States

  • Children's Hospital of Shanghai /ID# 262356

    RECRUITING

    Shanghai, Shanghai Municipality, 200062, China

  • Christchurch Hospital. /ID# 262577

    RECRUITING

    Christchurch, Canterbury, 8011, New Zealand

  • Clinical Research Investigator Group, LLC /ID# 262357

    RECRUITING

    Bayamón, 00960, Puerto Rico

  • Clinical Research Puerto Rico /ID# 279595

    RECRUITING

    San Juan, 00909-1711, Puerto Rico

  • Cliniques Universitaires UCL Saint-Luc /ID# 261741

    RECRUITING

    Brussels, Brussels Capital, 1200, Belgium

  • Connecticut Children's Medical Center - Hartford /ID# 262256

    RECRUITING

    Hartford, Connecticut, 06106, United States

  • Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 262811

    RECRUITING

    London, Greater London, E1 2ES, United Kingdom

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico /ID# 275276

    RECRUITING

    Milan, 20122, Italy

  • Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 262384

    RECRUITING

    San Giovanni Rotondo, Foggia, 71013, Italy

  • Galileo Medical Research Ltda /ID# 262602

    RECRUITING

    Juiz de Fora, Minas Gerais, 36033-318, Brazil

  • Gastromed Sp. z o.o /ID# 262367

    RECRUITING

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

  • General Hospital of Chest Diseases of Athens SOTIRIA /ID# 261790

    RECRUITING

    Athens, Attica, 11527, Greece

  • Guangzhou Medical University Affiliated Women and Children's Medical Center /ID# 262596

    RECRUITING

    Guangzhou, Guangdong, 510620, China

  • Henan Children's Hospital Zhengzhou Children's Hospital /ID# 262300

    RECRUITING

    Zhengzhou, Henan, 450018, China

  • Hopitaux de Paris (AP-HP) - Hopital Robert Debre - CHU /ID# 262308

    RECRUITING

    Paris, 75019, France

  • Hospices Civils de Lyon - Hôpital Femme Mère Enfant /ID# 263422

    RECRUITING

    Bron, Rhone, 69500, France

  • Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 262226

    RECRUITING

    Ferrol, A Coruna, 15405, Spain

  • Hospital Clinico Universitario Lozano Blesa /ID# 262227

    COMPLETED

    Zaragoza, 50009, Spain

  • Hospital Pequeno Príncipe /ID# 262600

    RECRUITING

    Curitiba, Paraná, 80250-060, Brazil

  • Hospital Regional Universitario de Malaga /ID# 262228

    RECRUITING

    Málaga, 29011, Spain

  • Hospital Sant Joan de Deu /ID# 262599

    RECRUITING

    Esplugues de Llobregat, Barcelona, 08950, Spain

  • Hospital Sirio Libanes /ID# 262670

    RECRUITING

    São Paulo, 01308-050, Brazil

  • Hospital Universitario Virgen del Rocio /ID# 262712

    RECRUITING

    Seville, 41013, Spain

  • Hospital Universite Enfants Reine Fabiola /ID# 261744

    RECRUITING

    Brussels, 1020, Belgium

  • Hunan Children's Hospital /ID# 262512

    RECRUITING

    Changsha, Hunan, 410007, China

  • IWK Health Center /ID# 262543

    RECRUITING

    Halifax, Nova Scotia, B3K 6R8, Canada

  • Icahn School of Medicine at Mount Sinai /ID# 262216

    RECRUITING

    New York, New York, 10029, United States

  • Indiana University Health Riley Hospital for Children /ID# 262215

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Institute of Science Tokyo Hospital /ID# 262510

    RECRUITING

    Bunkyo-ku, Tokyo, 113-8519, Japan

  • Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 262366

    RECRUITING

    Warsaw, Masovian Voivodeship, 04-730, Poland

  • Irmandade da Santa Casa de Misericordia de Porto Alegre /ID# 262601

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90020-090, Brazil

  • Jiangxi Provincial Children's Hospital /ID# 262295

    RECRUITING

    Nanchang, Jiangxi, 330006, China

  • Kurume University Hospital /ID# 262455

    RECRUITING

    Kurume-shi, Fukuoka, 830-0011, Japan

  • Linkou Chang Gung Memorial Hospital /ID# 261696

    RECRUITING

    Taoyuan, 333, Taiwan

  • Lucile Packard Children's Hospital /ID# 262193

    RECRUITING

    Palo Alto, California, 94304, United States

  • MNGI Digestive Health, P. A. /ID# 262204

    RECRUITING

    Minneapolis, Minnesota, 55413-2195, United States

  • Miyagi Children's Hospital /ID# 262459

    RECRUITING

    Sendai, Miyagi, 989-3126, Japan

  • Monash Health - Monash Medical Centre /ID# 262878

    RECRUITING

    Clayton, Victoria, 3168, Australia

  • National Center For Child Health And Development /ID# 262456

    RECRUITING

    Setagaya City, Tokyo, 157-8535, Japan

  • National Taiwan University Hospital /ID# 261695

    RECRUITING

    Taipei City, Taipei, 100, Taiwan

  • Norfolk and Norwich University Hospitals NHS Foundation Trust /ID# 262778

    RECRUITING

    Norwich, Norfolk, NR4 7UY, United Kingdom

  • OSF St. Francis Medical Center /ID# 262192

    RECRUITING

    Peoria, Illinois, 61637-0001, United States

  • Osaka Women's and Children's Hospital /ID# 262549

    RECRUITING

    Izumi-Shi, Osaka, 594-1101, Japan

  • Ospedale Pediatrico Bambino Gesù /ID# 262379

    RECRUITING

    Rome, Roma, 00165, Italy

  • Perth Children'S Hospital /ID# 272905

    RECRUITING

    Perth, Western Australia, 6009, Australia

  • Puerto Rico Health Institute /ID# 262358

    RECRUITING

    Dorado, 00646, Puerto Rico

  • Queensland Children's Hospital /ID# 262351

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

  • Rocco & Nazato Servicos Medicos /ID# 262485

    RECRUITING

    São Paulo, São Paulo, 04543-011, Brazil

  • Royal Hospital for Children and Young People /ID# 262388

    RECRUITING

    Edinburgh, EH16 4TJ, United Kingdom

  • Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 262502

    RECRUITING

    Shanghai, Shanghai Municipality, 200065, China

  • Saga University Hospital /ID# 262753

    RECRUITING

    Saga, Saga-ken, 849-8501, Japan

  • Saitama Children's Medical Center /ID# 262461

    RECRUITING

    Saitama-shi, Saitama, 330-8777, Japan

  • Samsung Medical Center /ID# 262323

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

  • Seoul National University Hospital /ID# 262324

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • Sheffield Children's Hospital NHS Foundation Trust /ID# 261832

    RECRUITING

    Sheffield, England, S10 2TH, United Kingdom

  • Shengjing Hospital of China Medical University /ID# 262301

    RECRUITING

    Shenyang, Liaoning, 110022, China

  • Specialized Hospital For Active Treatment Of Children Diseases Prof. Ivan Mitev /ID# 262589

    RECRUITING

    Sofia, 1606, Bulgaria

  • Starship Child Health /ID# 262576

    COMPLETED

    Auckland, 0629, New Zealand

  • Sydney Children's Hospital /ID# 262352

    RECRUITING

    Randwick, New South Wales, 2031, Australia

  • The Children's Hospital of Zhejiang University School of Medicine /ID# 262337

    RECRUITING

    Hangzhou, Zhejiang, 310003, China

  • The Sixth Affiliated Hospital of Sun Yat-sen University /ID# 272807

    RECRUITING

    Guangzhou, Guangdong, 510655, China

  • Tokyo Metropolitan Children's Medical Center /ID# 262550

    RECRUITING

    Fuchu-shi, Tokyo, 183-8561, Japan

  • Toyama Prefectural Central Hospital /ID# 262739

    RECRUITING

    Toyama, Toyama, 930-8550, Japan

  • Tsujinaka Hospital - Kashiwanoha /ID# 262454

    RECRUITING

    Kashiwa-shi, Chiba, 277-0871, Japan

  • UCL Namur University Hospital, Site Sainte-Elisabeth /ID# 261750

    RECRUITING

    Namur, 5000, Belgium

  • UCSF Benioff Children's Hospital - Oakland /ID# 262217

    RECRUITING

    Oakland, California, 94609, United States

  • UH Cleveland Medical Center /ID# 262188

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • UMHAT Sveti Georgi /ID# 262590

    RECRUITING

    Plovdiv, 4002, Bulgaria

  • Univ NC Chapel Hill /ID# 262198

    RECRUITING

    Chapel Hill, North Carolina, 27514-4220, United States

  • Universitair Ziekenhuis Leuven /ID# 261740

    RECRUITING

    Leuven, Vlaams-Brabant, 3000, Belgium

  • University General Hospital of Heraklion PA.G.N.I /ID# 261791

    RECRUITING

    Heraklion, Crete, 71500, Greece

  • Uza /Id# 261745

    RECRUITING

    Edegem, Antwerpen, 2650, Belgium

  • Yonsei University Health System Severance Hospital /ID# 262721

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03722, South Korea

Conditions

Explore the condition pages connected to this study.