Targeted fungus fight: a genetic approach to taming Crohn's

NCT ID NCT04966585

Summary

This study tested whether treating a specific gut fungus with the antifungal drug posaconazole could reduce inflammation in people with active Crohn's disease who have a particular genetic risk (CARD9 S12N). It was a small, placebo-controlled trial that looked for improvements in gut lining and symptoms. The trial was terminated early.

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Contacts and locations

Locations

  • Cedars-Sinai Medical Center (CSMC)

    Los Angeles, California, 90048, United States

  • Mayo Clinic

    Rochester, Minnesota, 55901, United States

Conditions

Explore the condition pages connected to this study.