Can a simple blood thinner save teens from deadly clots?

NCT ID NCT06628778

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the blood thinner enoxaparin can prevent dangerous blood clots in teens who are critically ill in the intensive care unit. About 800 high-risk teens will receive either enoxaparin or a placebo. The goal is to see if the drug reduces clots without causing serious bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Enoxaparin (a blood thinner)

What this could lead to

If it works, this could provide a proven way to prevent dangerous blood clots in hospitalized teens, reducing complications and saving lives.

What could go wrong

This is a first-of-its-kind trial in children, so results are uncertain. Enoxaparin also raises bleeding risk, which must be carefully balanced against any benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Critical Illness venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins All Children"s Hospital

    St. Petersburg, Florida, 33704, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact