Creatine may shield breast cancer patients from 'Chemo Brain'
NCT ID NCT07372144
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether taking creatine supplements daily can prevent or reduce the memory and thinking problems that often come with chemotherapy. About 227 women with early-stage breast cancer will receive either creatine or a placebo, starting before chemo and continuing for a year after. Researchers will track cognitive function through tests and questionnaires, along with brain scans and blood samples.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
creatine monohydrate (5 g per day oral supplement)
What this could lead to
If it works, this could offer a simple, safe way to protect thinking and memory during chemotherapy for breast cancer patients.
What could go wrong
This is a large Phase 3 trial, but it is not yet recruiting. Creatine may not prevent cognitive decline, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Instituto D'Or de Pesquisa e Ensino de São Paulo
São Paulo, São Paulo, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••