New CPAP strategy aims to help preterm lungs grow stronger

NCT ID NCT06123143

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a structured plan for slowly removing breathing support (CPAP) from preterm infants born before 30 weeks. The goal is to see if keeping babies on CPAP until a specific age reduces breathing problems and lung damage. About 130 infants will be randomly assigned to either the structured plan or standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

structured CPAP weaning protocol

What this could lead to

If successful, this could establish a better way to wean preterm infants off breathing support, potentially reducing chronic lung disease and hospital stays.

What could go wrong

This is a relatively small, early-stage study (130 infants) comparing a structured protocol to standard care. Results may not apply to all hospitals or infants, and the protocol may not reduce weaning failure as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neonatal respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Palomar Medical Center Rady NICU

    RECRUITING

    Escondido, California, 92029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rady Children's Hospital-San Diego

    RECRUITING

    San Diego, California, 92123, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rancho Springs Medical Center Rady NICU

    RECRUITING

    Murrieta, California, 92562, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Scripps La Jolla Rady NICU

    RECRUITING

    La Jolla, California, 92037, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California, San Diego Jacobs Medical Center

    RECRUITING

    La Jolla, California, 92037, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••