New COVID-19 booster vaccine shows promise in early trial

NCT ID NCT05541861

First seen Jan 18, 2026 · Last updated May 04, 2026 · Updated 16 times

Summary

This early-stage trial tested a new RNA-based COVID-19 booster vaccine in 383 healthy adults who had already received a COVID-19 vaccine. The main goal was to see if the vaccine was safe and to find the best dose. Researchers measured side effects and immune responses after one or two doses.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alliance for Multispecialty Research, LLC

    Tempe, Arizona, 85281, United States

  • Alliance for Multispecialty Research, LLC

    Knoxville, Tennessee, 37909, United States

  • Alliance for Multispecialty Research, LLC (Kansas)

    Kansas City, Missouri, 64114, United States

  • CTI Clinical Research Center

    Cincinnati, Ohio, 45212, United States

  • California Research Foundation

    San Diego, California, 92123, United States

  • Cenexel RCA (Research Centers of America)

    Hollywood, Florida, 33024, United States

  • Clinical Research Consulting, LLC

    Milford, Connecticut, 06460, United States

  • Clinical Trials of Texas, LLC / Flourish Research

    San Antonio, Texas, 78229, United States

  • DM Clinical Research

    Tomball, Texas, 77375, United States

  • Diablo Clinical Research, Inc.

    Walnut Creek, California, 94598, United States

  • Endeavor Clinical Trials, LLC

    San Antonio, Texas, 78229, United States

  • Finger Lakes Clinical Research

    Rochester, New York, 14618, United States

  • Great Lakes Clinical Trials LLC - Andersonville

    Chicago, Illinois, 60640, United States

  • Hoag Hospital

    Newport Beach, California, 92663, United States

  • Johnson County Clin-Trials, Inc. (JCCT)

    Lenexa, Kansas, 66219, United States

  • Research Institute of South Florida, Inc.

    Miami, Florida, 33173, United States

  • University of Kentucky Center for Clinical and Translational Science (outpatient clinic)

    Lexington, Kentucky, 40536, United States

Conditions

Explore the condition pages connected to this study.