Pandemic puzzle: COVID-19's hidden impact on pregnancy revealed
NCT ID NCT05197621
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study at Johns Hopkins Hospital is looking at how COVID-19 infection and mRNA vaccines (Pfizer or Moderna) affect pregnant women and their newborns. Researchers will collect blood, placenta, and breast milk samples from 300 participants to study immune responses and pregnancy outcomes. The goal is to fill knowledge gaps since pregnant women were not included in initial vaccine trials.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mRNA COVID-19 vaccine (Pfizer or Moderna)
What this could lead to
If successful, this study could provide crucial data on how COVID-19 vaccines work in pregnant women and their babies, helping guide future vaccine recommendations.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test a cure or therapy. Results may be limited by the small sample size and single location.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
Contact
Contact
Contact
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••