Pandemic puzzle: COVID-19's hidden impact on pregnancy revealed

NCT ID NCT05197621

Recruiting now Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study at Johns Hopkins Hospital is looking at how COVID-19 infection and mRNA vaccines (Pfizer or Moderna) affect pregnant women and their newborns. Researchers will collect blood, placenta, and breast milk samples from 300 participants to study immune responses and pregnancy outcomes. The goal is to fill knowledge gaps since pregnant women were not included in initial vaccine trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mRNA COVID-19 vaccine (Pfizer or Moderna)
What this could lead to: If successful, this study could provide crucial data on how COVID-19 vaccines work in pregnant women and their babies, helping guide future vaccine recommendations.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test a cure or therapy. Results may be limited by the small sample size and single location.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COVID-19 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

COVID-19 Pregnancy Complications, Infectious

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID-19 PREGNANCY; INFECTION

Contacts and locations

Locations

Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21287, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.