Age may alter vaccine immunity: new study investigates
NCT ID NCT04852289
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times
Summary
This study looks at how the immune systems of younger and older adults respond to Pfizer or Moderna COVID-19 vaccines. Researchers will collect blood samples from 78 healthy volunteers over two years to measure specific T-cell responses. The goal is to understand if age changes how well the vaccine works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal how age impacts immune response to COVID-19 vaccines, helping improve future vaccine strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It only measures immune markers and may not lead to direct health changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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NIH/NIA/Biomedical Research Center at Johns Hopkins Bayview campus
Baltimore, Maryland, 21244, United States
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National Institute of Aging, Clinical Research Unit
Baltimore, Maryland, 21224, United States
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