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Can a pill stop COVID-19 before it starts?

NCT ID NCT05897541

Prevention Sponsor: Shionogi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers are testing whether an antiviral tablet called S-217622 can prevent symptomatic COVID-19 in people who live with someone who has symptoms. The trial enrolls household contacts of a person with symptomatic COVID-19 and gives them either the antiviral or a placebo for a short period. The main goal is to see how many people in each group test positive for SARS-CoV-2 and develop COVID-19 symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
S-217622, an experimental antiviral tablet
What this could lead to
If it works, people exposed to COVID-19 at home could take a short course of tablets to avoid getting sick, similar to how Tamiflu is used for flu.
What could go wrong
The antiviral may not prevent enough infections to be useful, or it may only work against certain variants. Like any drug, it can cause side effects, and a phase 3 trial is needed to know if benefits outweigh risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

3,701 people

The number who actually took part.

Started

Jun 2023

Finished

Sep 2024

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Index Participants Only 1 index participant from each household will be enrolled in the study. Participants are eligible to be included as an index participant if all of the following criteria apply: 1. Pediatric participants or adult participants (of any age) 2. The index participant must: 1. Have at least 1 COVID-19 symptom within 24 hours before the index participant providing informed consent. COVID-19 symptom(s) must be deemed by the investigator as related to the current SARS-CoV-2 infection (not related to preexisting comorbidities) or deemed as preexisting and worsened due to SARS-CoV-2 infection. 2. Must have positive SARS-CoV-2 test (a nucleic acid amplification test or antigen test) from any respiratory tract specimen from a sample collected prior to randomization of the participant 3. Must have a potential study participant who can participate in the study after onset of COVID-19 symptoms in an index participant Study Participants Multiple study participants from the same household are allowed to be enrolled in the study. The study intervention randomization will be performed based at the study participant's level. Participants will be eligible to be included in the study only if all of the following criteria apply: 1. ≥ 12 years of age at the time of signing the informed consent 2. Has a negative screening for SARS-CoV-2 infection, as determined by SARS-CoV-2 test (a nucleic acid amplification test or antigen test) from any respiratory tract specimen (for example, oropharyngeal, nasopharyngeal or nasal swab, or saliva). 3. Has lived in household with index participant and will continue to live in same household and share common areas such as dining rooms and bathrooms until the end of the study 4. Must not be considered by the investigator or subinvestigator to have SARS-CoV-2 infection and: 1. No measured fever at Screening (defined as body temperature ≥ 38.0°Celsius \[C\] per tympanic or rectal thermometer or ≥ 37.5°C per axillary, oral, or forehead/temporal thermometer) 2. No COVID-19 symptoms at Screening (if a participant has COVID-19-like symptoms caused by comorbidities, only 1 symptom will be allowed) 5. Capable and willing to complete a participant diary 6. a. Male participants: Participants with partners that are woman of childbearing potential (WOCBP) must agree to use effective contraception. Participants with pregnant partners must agree to use effective contraception. b. Female participants: A female participant is eligible to participate if she is not pregnant or breastfeeding, and the following conditions applies: * Is not a WOCBP or * All of the following apply: * Is a WOCBP and using a contraceptive method that is effective as described in the protocol. * A WOCBP must have a negative urine pregnancy test within 24 hours before the first dose of study intervention period. * If a urine pregnancy test cannot be confirmed as negative (for example, an ambiguous result), a serum pregnancy test must be negative. * Additional requirements for pregnancy testing during and after study intervention as described in the protocol. * The investigator/subinvestigator will review medical history, menstrual history, and recent sexual activity to decrease the risk of inclusion of a woman with an early undetected pregnancy. 7. Participant must be randomized ≤ 72 hours from onset of COVID-19 symptoms in the index participant. Exclusion Criteria: Study Participants: Participants will be excluded from the study if any of the following criteria apply: 1. Tested positive for SARS-CoV-2 in the past 6 months. 2. Have an underlying disease requiring systemic corticosteroids (excluding topical), antipyretics/analgesics, or immunosuppressive agents. 3. Known current renal impairment defined as creatinine clearance \< 30 milliliters/minute by Cockcroft Gault or requiring dialysis. 4. Participants with severe liver dysfunction, such as known history of cirrhosis or liver decompensation (including ascites, variceal bleeding, or hepatic encephalopathy). 5. Received approved, authorized, or investigational convalescent plasma, or other anti- SARS-CoV-2 biologic products within 3 months of the Screening Visit 6. Received approved, authorized, or investigational anti-SARS-CoV-2 monoclonal antibodies (mAbs) in the last 6 months. 7. Received any SARS-CoV-2 vaccine within 6 months prior to the Screening Visit or is expected to receive a SARS-CoV-2 vaccine or other approved, authorized, or investigational postexposure prophylaxis treatments until the end of the study. 8. Participants who have used any of the following drugs within 14 days prior to enrollment: 1. Strong cytochrome P450 (CYP) 3A inducer 2. Products containing St. John's wort 9. Exposed to an investigational drug within 30 days or 5 half-lives of the drug prior to the Screening Visit. 10. Positive urine pregnancy test at Screening Visit or are lactating. 11. Known allergy/sensitivity or any hypersensitivity to components of S-217622 or placebo for S-217622. 12. Any condition or circumstance that, in the opinion of the investigator or subinvestigator, would compromise the safety of the participant or the quality of the study data. Note: Other protocol-defined Inclusion/Exclusion criteria may apply.

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SARS-CoV-2 infection

Contacts and locations

Locations

  • ACRC Trials - Carrollton - Hunt - PPDS

    Carrollton, Texas, 75010, United States

  • Absolute Clinical Research, LLC

    Phoenix, Arizona, 85051-5775, United States

  • Accel Research Site - Achieve - Birmingham - ERN - PPDS

    Birmingham, Alabama, 35216, United States

  • Accel Research Sites - Nona Pediatric Center - ERN - PPDS

    Orlando, Florida, 32829-8070, United States

  • Advances In Health Inc

    Pearland, Texas, 77584-8075, United States

  • Alina Clinical Trials, LLC

    Dallas, Texas, 75225-6301, United States

  • Alliance for Multispecialty Research LLC - Roy

    Roy, Utah, 84067-9108, United States

  • Alliance for Multispecialty Research, LLC - Kaysville - PPDS

    Kaysville, Utah, 84037-4300, United States

  • Alma Research

    Miami, Florida, 33165, United States

  • American Research Centers of Florida

    Pembroke Pines, Florida, 33027-1717, United States

  • Apex Research Group

    Fair Oaks, California, 95628-2501, United States

  • Ark Clinical Research - Long Beach - ClinEdge - PPDS

    Long Beach, California, 90815-2521, United States

  • Ascada Research LLC

    Fullerton, California, 92835-4127, United States

  • Balanced Life Health Care Solutions - SKYCRNG - PPDS

    Lawrenceville, Georgia, 30046-8703, United States

  • Bayside Clinical Research-West Tampa

    Tampa, Florida, 33607, United States

  • BioClinical Research Alliance

    Miami, Florida, 33155-6542, United States

  • C & R Research Services USA

    Houston, Texas, 77022, United States

  • CCM Clinical Research Group

    Miami, Florida, 33133-4231, United States

  • CTMD Research, Inc. Palm Springs - Hunt - PPDS

    Palm Springs, Florida, 33406-7671, United States

  • Care United Research, LLC - Elligo - PPDS

    Forney, Texas, 75126-4174, United States

  • Care and Cure Clinic

    Houston, Texas, 77090-1243, United States

  • Central Alabama Research

    Birmingham, Alabama, 35209-8401, United States

  • Central Florida Internists - Conway

    Orlando, Florida, 32812-7331, United States

  • Centro Médico San Nicolás Grupo Oroño

    San Nicolás de los Arroyos, Buenos Aires, B2900, Argentina

  • Child Healthcare Associates - East Syracuse

    East Syracuse, New York, 13057-9305, United States

  • Clinical Associates in Research Therapeutics of America

    San Antonio, Texas, 78212-4829, United States

  • Clinical Trials Management Services, LLC

    Thousand Oaks, California, 91360, United States

  • Clinical Trials of South Carolina - ClinEdge - PPDS

    Moncks Corner, South Carolina, 29461-5017, United States

  • Clínica Mayo de U.M.C.B. S.R.L

    San Miguel de Tucumán, Tucumán Province, T4000IHE, Argentina

  • Clínica Privada Independencia

    Munro, Buenos Aires, 1605, Argentina

  • Coastal Pediatric Associates

    Charleston, South Carolina, 29414-5834, United States

  • Combined Research Orlando Phase I-IV LLC

    Orlando, Florida, 32807-3555, United States

  • Continental Clinical Research, LLC

    Miami, Florida, 33144-4273, United States

  • Cullman Clinical Trials

    Cullman, Alabama, 35055-1902, United States

  • Cyn3rgy Research - ClinEdge - PPDS

    Gresham, Oregon, 97030-8319, United States

  • DCT-McAllen Primary Care Research, LLC dba Discove

    McAllen, Texas, 78503-1397, United States

  • Denenchofu Family Clinic

    Ōta-ku, Tokyo Province, 145-0071, Japan

  • Eagle Clinical Research

    Chicago, Illinois, 60621-3116, United States

  • Entrust Clinical Research

    Miami, Florida, 33176-1530, United States

  • Epic Medical Research LLC - DeSoto

    DeSoto, Texas, 75115-2043, United States

  • Florida Research Center, Inc.

    Miami, Florida, 33144-2069, United States

  • Flourish Research - Leesburg - PPDS

    Leesburg, Florida, 34748-5077, United States

  • Flourish Research - Miami - PPDS

    Miami, Florida, 33186-9066, United States

  • Frontier Clinical Research - Scottdale

    Scottdale, Pennsylvania, 15683-2460, United States

  • Fujimaki Ear, Nose and Throat Clinic (Ent Clinic)

    Ichikawa-Shi, Chiba, 272-0143, Japan

  • Fujimino Emergency Hospital

    Miyoshi-machi, Iruma-gun, Saitama, 354-0044, Japan

  • Fukuda Medical Clinic

    Toda-shi, Saitama, 335-0015, Japan

  • GCP Global Clinical Professionals, LLC

    Miami, Florida, 33169-5732, United States

  • Global Health Clinical Trials

    Miami, Florida, 33165-2968, United States

  • Global Healthcare Clinic

    Chiyoda-Ku, Tokyo, 102-0083, Japan

  • Global Medical Research - M3 WR

    Dallas, Texas, 75224-2367, United States

  • Hamamatsu Medical Center

    Hamamatsu, Shizuoka, 432-8580, Japan

  • Hanoi University of Medicine - Clinical Trial Unit

    Quận Đống Đa, Ha Noi, Thu Do, 100000, Vietnam

  • Healthstar Research

    Hot Springs, Arkansas, 71913-8184, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202-2608, United States

  • Hitachi,Ltd.,Tsuchiura Medical & Health Care Center

    Tsuchiura, Ibaraki, 300-0012, Japan

  • Hope Clinical Trials

    Coral Gables, Florida, 33134-1642, United States

  • Hosokawa Surgical Clinic

    Nagoya-Shi Nakamura-Ku, Aiti, 453-0812, Japan

  • Hospital Interzonal General de Agudos Vicente Lopez Y Planes

    General Rodriguez, Buenos Aires, 1748, Argentina

  • Hospital Rawson

    Córdoba, 5000, Argentina

  • I.V.A.M. Clinical & Investigational Center

    Doral, Florida, 33126, United States

  • INECO Neurociencias Oroño

    Rosario, Santa Fe Province, S2000DTP, Argentina

  • Iizuka Hospital

    Iizuka-Shi, Hukuoka, 820-8505, Japan

  • Ikebukuro Higashiguchi Mame Clinic

    Toshima-ku, 170-0013, Japan

  • Instituto Médico Río Cuarto

    Río Cuarto, Córdoba Province, 5800, Argentina

  • Instituto Médico de la Fundación Estudios Clínicos

    Rosario, Santa Fe Province, S2013DTC, Argentina

  • Instituto de Investigaciones Clínicas Zárate

    Zárate, Buenos Aires, B2800DGH, Argentina

  • Invictus Clinical Research Group, LLC

    Coconut Creek, Florida, 33073-3458, United States

  • Irie Naika Syounika Iin

    Fukuoka, Fukuoka, 812-0053, Japan

  • Ivetmar Medical Group, LLC

    Miami, Florida, 33155-6542, United States

  • Japanese Red Cross Fukuoka Hospital

    Fukuoka, Hukuoka Province, 815-0082, Japan

  • KODAIRA Hospital

    Toda-Shi, Saitama, 335-0035, Japan

  • KU Wichita Center for Clinical Research

    Wichita, Kansas, 67214-3124, United States

  • Kaiseikai Kita Shin Yokohama Internal Medicine Clinic

    Yokohama, Kanagawa, 223-0059, Japan

  • Kamezawa Clinic

    Kasugai-Shi, Aiti, 486-0817, Japan

  • Kamoike Otolaryngology Clinic

    Kagoshima, Kagoshima-ken, 890-0063, Japan

  • Kanagawa Himawari Clinic

    Kawasaki-Shi, Kanagawa, 216-0006, Japan

  • Kasukabe Medical Center

    Kasukabe, Saitama, 344-8588, Japan

  • Kendall South Medical Center

    Miami, Florida, 33185-4082, United States

  • Kijima Kids Clinic

    Higashiokitama-gun, Yamagata, 999-0121, Japan

  • Kikuchi Internal clinic

    Maebashi, Gunma, 370-3573, Japan

  • LCC Medical Research - Miami - ClinEdge - PPDS

    Miami, Florida, 33126-1921, United States

  • Lapis Clinical Research-Denver

    Denver, North Carolina, 28037-8254, United States

  • Lee's Clinic

    Osaka, Osaka, 531-0073, Japan

  • Lynn Institute of The Rockies - ERN - PPDS

    Colorado Springs, Colorado, 80918-1662, United States

  • MIH Clinic Yoyogi

    Shibuya-Ku, Tokyo, 151-0051, Japan

  • Main Street Physicians Care - Waterway

    Little River, South Carolina, 29566, United States

  • Maruyama Tame Pediatrics

    Sapporo, Hokkaidô, 064-0821, Japan

  • MedQuest Translational Sciences

    Miami Lakes, Florida, 33016, United States

  • Medical Corporation Kojyokai Hirose Clinic

    Tokorozawa-Shi, Saitama, 359-1111, Japan

  • Medical Corporation Nakano Children's Clinic

    Yokohama, Kanagawa, 222-0012, Japan

  • Megumi Clinic

    Kasuyagun Shimemachi, Fukuoka, 811-2201, Japan

  • Meridian International Research

    Miami Lakes, Florida, 33014-6433, United States

  • Miami Clinical Research - ClinEdge - PPDS

    Miami, Florida, 33155, United States

  • Montana Medical Research

    Missoula, Montana, 59808, United States

  • Moriyama Otolaryngology

    Kagoshima, Kagoshima-ken, 890-0034, Japan

  • Morizono medical clinic

    Kitakyushu-shi, Hukuoka, 807-0072, Japan

  • Motosumiyoshi-ekimae Cocoromi Clinic

    Kawasaki-Shi, Kanagawa, 211-0025, Japan

  • Murasakibaru Tahara Hospital

    Kagoshima, Kagoshima-ken, 890-0082, Japan

  • Musashino Hospital

    Kodaira-Shi, Tokyo, 187-0031, Japan

  • NHO Okinawa Hospital

    Ginowan-Shi, Okinawa, 901-2214, Japan

  • NMMM PHARMEDICA Health Research Institute

    Lombardy East, Johannesburg, Gauteng, 2090, South Africa

  • Nagaoka Chuo General Hospital

    Nagaoka-Shi, Niigata, 940-8653, Japan

  • Nagata Hospital

    Yanagawa-Shi, Hukuoka, 832-0059, Japan

  • Nakayama Pediatric Clinic

    Nagasaki, 852-8133, Japan

  • Neighborhood Healthcare

    Escondido, California, 92025-4604, United States

  • New Horizon Medical Group, LLC

    Houston, Texas, 77065, United States

  • Newtown Clinical Research Centre

    City of Johannesburg, Gauteng, 2001, South Africa

  • Nishikasai ekimae Family Clinic

    Edogawa-ku, Tokyo, 134-0088, Japan

  • Nishioka Hospital

    Sapporo-Shi Toyohira-Ku, Hokkaidô, 062-0034, Japan

  • Nishiyamato Keiwa Hospital

    Naka, Ibaraki, 311-0133, Japan

  • Nozaki Clinical

    Musashino-Shi, Tokyo, 180-0022, Japan

  • Oceane7 Medical & Research Center, Inc.

    Miami, Florida, 33144-2155, United States

  • Okayama University Hospital

    Okayama, 700-8558, Japan

  • Olivo Medical and Wellness Center

    Chicago, Illinois, 60618-8101, United States

  • One of a Kind Clinical Research Center LLC

    Scottsdale, Arizona, 85258-4590, United States

  • Ormond Beach Clinical Research

    Ormond Beach, Florida, 32174-8196, United States

  • Osaka City Juso Hospital

    Osaka, 532-0034, Japan

  • Preferred Research Partners - ClinEdge - PPDS

    Little Rock, Arkansas, 72211-3868, United States

  • Premier Clinical Research Institute - Miami - ClinEdge - PPDS

    Miami, Florida, 33122-1335, United States

  • PriMed Clinical Research - ClinEdge - PPDS

    Dayton, Ohio, 45429-3658, United States

  • Progressive Medical Research - ClinEdge - PPDS

    Port Orange, Florida, 32127, United States

  • Progressive Medicine of the Triad, LLC

    Winston-Salem, North Carolina, 27103-1552, United States

  • Quality Research of South Florida

    Hialeah, Florida, 33016-1811, United States

  • Rancho Cucamonga Clinical Research

    Rancho Cucamonga, California, 91730-3062, United States

  • Renew Health Clinical Research, LLC

    Tampa, Florida, 33607-2529, United States

  • Research Institute of South Florida Inc

    Miami, Florida, 33173-4648, United States

  • Rinku General Medical Center

    Izumisano, Osaka, 598-0048, Japan

  • Rochester Clinical Research - ATLAS - Rochester - PPDS

    Rochester, New York, 14609-3173, United States

  • SPICA Clinical Research

    Columbia, South Carolina, 29223-6301, United States

  • Saint Hope Foundation Inc

    Bellaire, Texas, 77401-4500, United States

  • Sanatorio Allende S.A

    Córdoba, X5000JHQ, Argentina

  • Sanatorio Medico de Diagnostico Y Tratamiento

    Santa Fe, S3000FUJ, Argentina

  • Shimamura Memorial Hospital

    Nerima-Ku, Tokyo, 177-0051, Japan

  • Shiwa Chuo Syounika

    Shiwa-gun, 028-3318, Japan

  • Shizuka Medical Clinic

    Takasaki-shi, 370-0071, Japan

  • Shoda Hospital

    Annaka-Shi, Gunma, 379-0116, Japan

  • Smart Cures Clinical Research

    Rolling Hills Estates, California, 90274-7604, United States

  • Southwest Family Medicine Associates

    Dallas, Texas, 75235-1715, United States

  • Soyukai Medical Corporation Yamaguchi clinic

    Ōta-ku, 145-0063, Japan

  • Suita Municipal Hospital

    Suita, Ôsaka, 564-8567, Japan

  • Suncoast Research Group LLC - Flourish - PPDS

    Miami, Florida, 33135-1687, United States

  • Suto Hospital

    Annaka-shi, Gunma, 379-0016, Japan

  • Takahashi Medical Clinic

    Kokubunji-Shi, Tokyo, 185-0014, Japan

  • Takahashi Pediatric Clinic

    Kobe-Shi Nada-Ku, Hyôgo, 657-0846, Japan

  • Takinogawa Hospital

    Kita-ku, Tokyo, 114-0023, Japan

  • Tampa Bay Health Care

    Tampa, Florida, 33615, United States

  • Tashiro Endocrinolgy Clinic

    Fukuoka, Fukuoka, 814-0153, Japan

  • Teine Otolaryngology Clinic

    Sapporo, Hokkaidô, 006-0815, Japan

  • Terada Clinic Respiratory Medicine and General Practice

    Himeji-shi, Hyôgo, 670-0849, Japan

  • Toda Internal Medicine ＆ Neurology

    Akashi-Shi, Hyôgo, 674-0081, Japan

  • Tokyo Center Clinic

    Chuo-ku, Tokyo, 103-0028, Japan

  • Tokyo Shinagawa Hospital Social Medical Corporation Association Tokyokyojuno-kai

    Shinagawa-ku, Tokyo, 140-0011, Japan

  • Tomita Internal medicine clinic

    Fukuoka, Fukuoka, 810-0033, Japan

  • Torrance Clinical Research Institute

    Lomita, California, 90717-2101, United States

  • Toyama Rosai Hospital

    Uozu-Shi, Toyama, 937-0042, Japan

  • Tranquil Clinical Research

    Webster, Texas, 77598-3900, United States

  • Trident Clinical

    Sol Plaatjie, Northern Cape, 8301, South Africa

  • Tristar Clinical Investigations, P.C.

    Philadelphia, Pennsylvania, 19114-1030, United States

  • TrueBlue Clinical Research

    Brandon, Florida, 33511-4850, United States

  • Tsuchiura Beryl Clinic

    Tsuchiura-Shi, Ibaraki, 300-0062, Japan

  • Universal Medical and Research Center, LLC

    Coral Gables, Florida, 33134-1602, United States

  • Universal Medical and Research Center, LLC Homestead

    Homestead, Florida, 33030-6057, United States

  • University of Medicine Center, Ho Chi Minh City

    Ho Chi Minh City, 700000, Vietnam

  • University of Miami - 1150 NW 14th St

    Miami, Florida, 33136-1104, United States

  • University of Tsukuba Hospital

    Tsukuba, Ibaraki, 305-8576, Japan

  • University of the Ryukyus Hospital - 207 Uehara

    Okinawa-Shi, Okinawa, 903-0215, Japan

  • Uno Internal Medicine Respiratory Clinic

    Isesaki-Shi, Gunma, 372-0831, Japan

  • VIP Trials

    San Antonio, Texas, 78230, United States

  • Valencia Medical and Research Center

    Miami, Florida, 33165-3912, United States

  • Valley Institute of Research

    Fort Worth, Texas, 76164-9041, United States

  • Velocity Clinical Research - Covington - PPDS

    Gulfport, Mississippi, 39503-2637, United States

  • Vida Clinical Sites

    Dearborn Heights, Michigan, 48127-2234, United States

  • Voyage Medical - Michigan

    Canton, Michigan, 48188-2866, United States

  • WellNow Urgent Care & Research - Huber Heights

    Dayton, Ohio, 45424-4019, United States

  • Yokohama Municipal Citizens Hospital

    Yokohama, Kanagawa, 240-0062, Japan

  • Yoshida Clinic

    Suginami-ku, Tokyo, 167-0043, Japan

  • Yotsuya Naika

    Shinjuku-Ku, Tokyo, 160-0017, Japan

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