Major trial tests COVID booster shots for better protection

NCT ID NCT04955626

Completed Prevention Sponsor: BioNTech SE Source: ClinicalTrials.gov ↗

Summary

This large, completed study aimed to see if giving extra doses of the Pfizer-BioNTech COVID-19 vaccine to people who were already vaccinated was safe and effective. It involved over 16,000 healthy participants across multiple countries and tested different booster doses, including versions designed for newer virus variants. The main goal was to see if these extra shots could better prevent COVID-19 infection and severe illness over time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AMR Clinical

Mobile, Alabama, 36608, United States
AMR Clinical

Newton, Kansas, 67114, United States
AMR Clinical

Wichita, Kansas, 67207, United States
Accel Research Sites - Birmingham Clinical Research Unit

Birmingham, Alabama, 35216, United States
Accellacare

Cary, North Carolina, 27518, United States
Accellacare

Charlotte, North Carolina, 28211, United States
Accellacare

Hickory, North Carolina, 28601, United States
Accellacare

Raleigh, North Carolina, 27609, United States
Accellacare

Wilmington, North Carolina, 28401, United States
Accellacare

Winston-Salem, North Carolina, 27103, United States
Accellacare (formerly PMG Research of Wilmington, LLC)

Wilmington, North Carolina, 28401, United States
Accellacare - Salisbury

Salisbury, North Carolina, 28144, United States
Acevedo Clinical Research Associates

Miami, Florida, 33142, United States
Alliance for Multispecialty Research - Weisgarber Medical Park

Knoxville, Tennessee, 37909, United States
Alliance for Multispecialty Research, LLC

Tempe, Arizona, 85281, United States
Alliance for Multispecialty Research, LLC

Coral Gables, Florida, 33134, United States
Anaheim Clinical Trials, LLC

Anaheim, California, 92801, United States
Bayview Research Group, LLC

Valley Village, California, 91607, United States
Benaroya Research Institute at Virginia Mason

Seattle, Washington, 98101, United States
Benchmark Research

Austin, Texas, 78705, United States
Benchmark Research

Fort Worth, Texas, 76135, United States
Boston Medical Center

Boston, Massachusetts, 02118, United States
Botho Ke Bontle Health Services PTY LTD

Pretoria, Gauteng, 0184, South Africa
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
Bozeman Health Deaconess Hospital d/b/a Bozeman Health Clinical Research

Bozeman, Montana, 59715, United States
CEPIC - Centro Paulista de Investigação Clínica

São Paulo, 04266-010, Brazil
California Research Foundation

San Diego, California, 92123, United States
Centricity Research Columbus Ohio Multispecialty

Columbus, Ohio, 43213, United States
Cincinnati Children's Hospital

Cincinnati, Ohio, 45229, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Clinical Alliance for Research & Education - Infectious Diseases (CARE-ID)

Annandale, Virginia, 22003, United States
Clinical Neuroscience Solutions Inc.

Memphis, Tennessee, 38119, United States
Clinical Neuroscience Solutions, Inc.

Orlando, Florida, 32801, United States
Clinical Neuroscience Solutions, Inc. dba CNS Healthcare

Jacksonville, Florida, 32256, United States
Clinical Research Associates Inc

Nashville, Tennessee, 37203, United States
Clinical Research Atlanta

Stockbridge, Georgia, 30281, United States
Clinical Research Consulting

Milford, Connecticut, 06460, United States
Clinical Research Professionals

Chesterfield, Missouri, 63005, United States
Clinical Trials of Texas, Inc.

San Antonio, Texas, 78229, United States
Clinical Trials of Texas, LLC

San Antonio, Texas, 78229, United States
Clinresco Centres

Kempton Park, Gauteng, 1619, South Africa
Collaborative Neuroscience Research, LLC

Long Beach, California, 90806, United States
Collaborative Neuroscience Research, LLC

Los Alamitos, California, 90720, United States
DM Clinical Research

Tomball, Texas, 77375, United States
DM Clinical Research - Bellaire

Houston, Texas, 77081, United States
DM Clinical Research - Kool Kids Pediatrics

Tomball, Texas, 77375, United States
Dayton Clinical Research

Dayton, Ohio, 45406, United States
Dayton Clinical Research

Dayton, Ohio, 45409, United States
Diablo Clinical Research, Inc.

Walnut Creek, California, 94598, United States
Dr A Jacovides & Partners Inc.

Midrand, Gauteng, 1685, South Africa
Duke University - Main Hospital and Clinics

Durham, North Carolina, 27703, United States
East-West Medical Research Institute

Honolulu, Hawaii, 96814, United States
Gallup Indian Medical Center

Gallup, New Mexico, 87301, United States
HG Pediatrics

Houston, Texas, 77008, United States
HOPE Research Institute

Phoenix, Arizona, 85023, United States
Holston Medical Group

Bristol, Tennessee, 37620, United States
Holston Medical Group

Kingsport, Tennessee, 37660, United States
Hope Research Institute

Phoenix, Arizona, 85018, United States
IACT Health

Columbus, Georgia, 31904, United States
IKF Pneumologie GmbH & Co. KG

Frankfurt, 60596, Germany
IMA Clinical Research San Antonio

San Antonio, Texas, 78229, United States
IMA Clinical Research Warren

Warren Township, New Jersey, 07059, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Indago Research & Health Center, Inc

Hialeah, Florida, 33012, United States
Innovo Research - Austin Regional Clinic

Austin, Texas, 78726, United States
J. Lewis Research, Inc. / Foothill Family Clinic

Salt Lake City, Utah, 84109, United States
J. Lewis Research, Inc. / Foothill Family Clinic South

Salt Lake City, Utah, 84121, United States
Jacksonville Center for Clinical Research

Jacksonville, Florida, 32216, United States
Johns Hopkins Bayview Medical Center

Baltimore, Maryland, 21224, United States
Johns Hopkins Center for American Indian Health

Chinle, Arizona, 86503, United States
Johns Hopkins Center for American Indian Health

Whiteriver, Arizona, 85941, United States
Johns Hopkins Center for American Indian Health

Gallup, New Mexico, 87301, United States
Johns Hopkins Center for American Indian Health

Shiprock, New Mexico, 87420, United States
Jongaie Research

Pretoria, 0183, South Africa
Kaiser Permanente Center for Health Research

Portland, Oregon, 97227, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kaiser Permanente Oakland

Oakland, California, 94611, United States
Kaiser Permanente Santa Clara

Santa Clara, California, 95051, United States
Kaiser Permenente Medical Center Infectious Disease

Los Angeles, California, 90027, United States
Kentucky Pediatric/ Adult Research

Bardstown, Kentucky, 40004, United States
Lehigh Valley Health Network/Network Office of Research and Innovation

Allentown, Pennsylvania, 18102, United States
Lillestol Research

Fargo, North Dakota, 58104, United States
Limpopo Clinical Research Initiative

Thabazimbi, Limpopo, 0380, South Africa
LinQ Research, LLC

Pearland, Texas, 77584, United States
Louisiana State University Health Sciences Shreveport

Shreveport, Louisiana, 71101, United States
Lynn Institute of Denver

Aurora, Colorado, 80012, United States
Lynn Institute of Norman

Norman, Oklahoma, 73072, United States
M3 Wake Research, Inc.

Raleigh, North Carolina, 27612, United States
Main Street Physician's Care

Little River, South Carolina, 29566, United States
Medical Affiliated Research Center

Huntsville, Alabama, 35801, United States
Meridian Clinical Research

Savannah, Georgia, 31406, United States
Meridian Clinical Research

Cincinnati, Ohio, 45246, United States
Meridian Clinical Research LLC

Binghamton, New York, 13901, United States
Meridian Clinical Research, LLC

Cincinnati, Ohio, 45219, United States
Methodist Physicians Clinic/CCT Research

Fremont, Nebraska, 68025, United States
Michigan Center of Medical Research (MICHMER)

Farmington Hills, Michigan, 48334, United States
NYU Langone Health

New York, New York, 10016, United States
Newtown Clinical Research

Johannesburg, Gauteng, 2113, South Africa
North Alabama Research Center

Athens, Alabama, 35611, United States
North Texas Infectious Diseases Consultants, P.A

Dallas, Texas, 75246, United States
Northern Navajo Medical Center

Shiprock, New Mexico, 87420, United States
Obras Sociais Irma Dulce

Salvador, Estado de Bahia, 40.415-006, Brazil
Ochsner Clinic Foundation

New Orleans, Louisiana, 70121, United States
Paradigm Clinical Research Centers, Inc

Redding, California, 96001, United States
PharmQuest Life Sciences, LLC

Greensboro, North Carolina, 27408, United States
PriMED Clinical Research

Dayton, Ohio, 45419, United States
Quality Clinical Research

Omaha, Nebraska, 68114, United States
Renu Garg, MD Pediatrics

Houston, Texas, 77008, United States
Research Building

Wenatchee, Washington, 98801, United States
Research Centers of America ( Hollywood )

Hollywood, Florida, 33024, United States
Rochester Clinical Research, Inc.

Rochester, New York, 14609, United States
SCR of Texas, LLC

Keller, Texas, 76248, United States
SMS Clinical Research

Mesquite, Texas, 75149, United States
SUNY Upstate Medical University

Syracuse, New York, 13215, United States
Senders Pediatrics

South Euclid, Ohio, 44121, United States
Sheba Medical Center

Ramat Gan, Central District, 5262100, Israel
Solaris Clinical Research

Meridian, Idaho, 83646, United States
South Jersey Infectious Disease

Somers Point, New Jersey, 08244, United States
Studienzentrum Dr. Keller

Frankfurt, 60389, Germany
Sundance Clinical Research

St Louis, Missouri, 63141, United States
Synergy Biomed Research Institute

East London, Eastern Cape, 5201, South Africa
TREAD Research

Cape Town, Parow, 7500, South Africa
Tekton Research, Inc

Austin, Texas, 78745, United States
The Pain Center of Arizona

Phoenix, Arizona, 85018, United States
Tiervlei Trial Centre

Cape Town, Western Cape, 7530, South Africa
Trinity Clinical Research

Tullahoma, Tennessee, 37388, United States
UC Davis Medical Center

Sacramento, California, 95817, United States
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Iowa

Iowa City, Iowa, 52242, United States
University of Massachusetts Chan Medical School

Worcester, Massachusetts, 01655, United States
University of Rochester Medical Center

Rochester, New York, 14642, United States
University of Rochester Medical Center- Kari Steinmetz

Rochester, New York, 14642, United States
VA Northeast Ohio Healthcare System

Cleveland, Ohio, 44106, United States
Van Tran Family Practice

Houston, Texas, 77008, United States
Velocity Clinical Research, Cleveland

Cleveland, Ohio, 44122, United States
Velocity Clinical Research, Covington

Gulfport, Mississippi, 39503, United States
Velocity Clinical Research, Los Angeles

Los Angeles, California, 90057, United States
Velocity Clinical Research, Norfolk

Norfolk, Nebraska, 68701, United States
Velocity Clinical Research, North Hollywood

North Hollywood, California, 91606, United States
Velocity Clinical Research, Omaha

Omaha, Nebraska, 68134, United States
Velocity Clinical Research, Providence

East Greenwich, Rhode Island, 02818, United States
Velocity Clinical Research, Sioux City

Sioux City, Iowa, 51106, United States
Velocity Clinical Research, Vestal

Vestal, New York, 13850, United States
Ventavia Research Group

Fort Worth, Texas, 76104, United States
Ventavia Research Group, LLC

Houston, Texas, 77008, United States
Virginia Research Center

Midlothian, Virginia, 23114, United States
Wake Research - Clinical Research Center of Nevada, LLC

Las Vegas, Nevada, 89106, United States
Wenatchee Valley Hospital

Wenatchee, Washington, 98801, United States
Whiteriver Indian Hospital

Whiteriver, Arizona, 85941, United States
Whiteriver Indian Hospital- Garrett Building

Whiteriver, Arizona, 85941, United States
Worthwhile Clinical Trials

Benoni, Gauteng, 1501, South Africa
Yale Center for Clinical Investigation

New Haven, Connecticut, 06519, United States
Yale University School of Medicine

New Haven, Connecticut, 06510, United States
Yale-New Haven Hospital

New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.

COVID-19 SARS-COV-2 INFECTION