Booster battle: moderna vs novavax for fourth COVID shot

NCT ID NCT05658523

First seen Jan 07, 2026 · Last updated May 09, 2026 · Updated 19 times

Summary

This study tests two different COVID-19 booster vaccines—Moderna's bivalent mRNA and Novavax's protein-based—in 496 healthy adults who have already had three doses. The goal is to see which booster produces a stronger immune response and causes fewer side effects. Participants will be followed for up to 30 months to track antibody levels and safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Royal Children's Hospital, Murdoch Children's Research Institute

    Melbourne, Victoria, 3052, Australia

Conditions

Explore the condition pages connected to this study.