Robot surgeon takes on knee replacements – will it beat the human hand?

NCT ID NCT04848896

Recruiting now Disease control Sponsor: Smith & Nephew, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a robot-assisted system (CORI) to conventional manual instruments for total knee replacement. About 140 participants will be randomly assigned to one of the two methods. The main goal is to see if the robot helps achieve more precise leg alignment after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CORI Robotics surgical navigation and burring system
What this could lead to: If successful, this could show that robot-assisted knee surgery leads to more accurate leg alignment than traditional methods.
What could go wrong: This is a relatively small, early-stage study focused on alignment, not long-term outcomes. The robot may not improve pain or function, and device-related risks include infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

avascular necrosis osteoarthritis rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHROPLASTY KNEE REPLACEMENT

Contacts and locations

Locations

Jishuitan Hospital, Beijing
RECRUITING

Beijing, 100035, China
North Shore Hospital
RECRUITING

Auckland, 0620, New Zealand
Northern Hospital
RECRUITING

Epping, 3076, Australia
The Prince of Wales Hospital
RECRUITING

Shatin, Hong Kong

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