Robot surgeon takes on knee replacements – will it beat the human hand?
NCT ID NCT04848896
First seen Mar 15, 2026 · Last updated Jun 23, 2026 · Updated 16 times
Summary
This study compares a robot-assisted system (CORI) to conventional manual instruments for total knee replacement. About 140 participants will be randomly assigned to one of the two methods. The main goal is to see if the robot helps achieve more precise leg alignment after surgery.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Jishuitan Hospital, Beijing
RECRUITINGBeijing, 100035, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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North Shore Hospital
RECRUITINGAuckland, 0620, New Zealand
Contact Email: •••••@•••••
Contact
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Northern Hospital
RECRUITINGEpping, 3076, Australia
Contact
Contact Email: •••••@•••••
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The Prince of Wales Hospital
RECRUITINGShatin, Hong Kong
Contact
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CORI Robotics surgical navigation and burring system
What this could lead to
If successful, this could show that robot-assisted knee surgery leads to more accurate leg alignment than traditional methods.
What could go wrong
This is a relatively small, early-stage study focused on alignment, not long-term outcomes. The robot may not improve pain or function, and device-related risks include infection or nerve damage.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.