Blood test may predict when colorectal cancer treatment fails

NCT ID NCT05487248

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether changes in tumor DNA found in the blood (ctDNA) can predict if chemotherapy is working in people with advanced colorectal cancer that no longer responds to standard treatments. About 103 participants will give blood samples and have regular scans to track their cancer. The goal is to find the best time and cutoff for ctDNA changes to signal when the cancer is progressing, which could help doctors adjust treatment sooner.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHIREC Delta

    Brussels, Belgium

  • CHU Ambroise Pare

    Mons, 7000, Belgium

  • CHU Poitiers

    Poitiers, France

  • Centre Georges François Leclerc

    Dijon, France

  • Cliniques Universitaires Saint Luc

    Woluwe-Saint-Lambert, 1200, Belgium

  • Hopital Franco-Britannique - Fondation Cognacq-Jay

    Levallois-Perret, 92300, France

  • Hopital St-Louis

    Paris, France

  • Hopital privé Jean Mermoz

    Lyon, France

  • ICANS Strasbourg

    Strasbourg, France

  • ICO Saint-Herblain

    Saint-Herblain, France

  • Institut Jules Bordet

    Anderlecht, 1070, Belgium

  • UZ Antwerpen

    Antwerp, Belgium