New shot aims to tame dangerous COPD attacks

NCT ID NCT05158387

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new injectable medication called tozorakimab can help people with COPD who keep having serious breathing flare-ups. About 1,172 adults who are former smokers and already on standard COPD inhalers will receive either the new drug or a placebo shot for a year. The main goal is to see if the drug can reduce the number of times participants need steroids, antibiotics, or hospitalization for their COPD.

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Contacts and locations

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Locations

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Sheffield, Alabama, 35660, United States
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Lincoln, California, 95648, United States
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Newport Beach, California, 92663, United States
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Northridge, California, 91324, United States
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Colorado Springs, Colorado, 80909, United States
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Newark, Delaware, 19713, United States
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Bay Pines, Florida, 33744, United States
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Cape Coral, Florida, 33990, United States
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Pensacola, Florida, 32503, United States
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Tampa, Florida, 33607, United States
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Winter Park, Florida, 32789, United States
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Macon, Georgia, 31201, United States
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Greenwood, Indiana, 46143, United States
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Bowling Green, Kentucky, 42101, United States
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White Marsh, Maryland, 21162, United States
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North Dartmouth, Massachusetts, 02747, United States
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Ann Arbor, Michigan, 48109, United States
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Farmington Hills, Michigan, 48336, United States
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Grand Rapids, Michigan, 49546, United States
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Buffalo, New York, 14203, United States
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The Bronx, New York, 10459, United States
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Toledo, Ohio, 43617, United States
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Oklahoma City, Oklahoma, 73104, United States
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Tulsa, Oklahoma, 74133, United States
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Philadelphia, Pennsylvania, 19140, United States
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Rock Hill, South Carolina, 29732, United States
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Amarillo, Texas, 79106, United States
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Boerne, Texas, 78006, United States
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Fort Worth, Texas, 76104, United States
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McKinney, Texas, 75069, United States
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Tomball, Texas, 77375, United States
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Webster, Texas, 77598, United States
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Williamsburg, Virginia, 23188, United States
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Cudahy, Wisconsin, 53110, United States
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Campbelltown, 2560, Australia
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Frankstown, 3199, Australia
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Macquarie University, 2109, Australia
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Melbourne, 3000, Australia
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Nedlands, 6009, Australia
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Southport, 4215, Australia
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Spearwood, 6163, Australia
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Wollongong, 2500, Australia
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Woodville South, 5011, Australia
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Blumenau, 89030-101, Brazil
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Botucatu, 18618-686, Brazil
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Brasília, 71681-603, Brazil
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Curitiba, 80440-220, Brazil
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Porto Alegre, 90035074, Brazil
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Porto Alegre, 9061-000, Brazil
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Porto Alegre, 91010-006, Brazil
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Rio de Janeiro, 22061-080, Brazil
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São Bernardo do Campo, 09750-420, Brazil
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São Paulo, 01323-903, Brazil
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São Paulo, 01409-001, Brazil
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São Paulo, 05403-000, Brazil
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Curicó, 3341643, Chile
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Santiago, 7500010, Chile
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Santiago, 7500657, Chile
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Santiago, 7500698, Chile
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Santiago, 8150000, Chile
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Santiago, 8241479, Chile
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Talca, 3465584, Chile
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Baotou, 014010, China
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Beijing, 100144, China
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Beijing, 101200, China
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Changchun, 130021, China
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Changde, 415000, China
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Changsha, 410015, China
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Chengdu, 610000, China
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Chengdu, 610031, China
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Chengdu, 610083, China
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Chongqing, 400013, China
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Chongqing, 400037, China
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Guangzhou, 510120, China
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Guangzhou, 510180, China
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Guangzhou, 510630, China
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Haikou, 570311, China
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Hangzhou, 310006, China
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Hefei, 230001, China
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Hohhot, 010010, China
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Kunming, 650032, China
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Linhai, 317000, China
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Nanchang, 330006, China
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Nanjing, 210006, China
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Ningbo, 315010, China
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Shanghai, 200002, China
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Shanghai, 200433, China
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Shanghai, 201199, China
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Shengyang, 110004, China
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Shenyang, 110016, China
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Shenzhen, 518020, China
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Shenzhen, 518053, China
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Shijiazhuang, 50051, China
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Suzhou, 215002, China
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Taiyuan, 030001, China
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Tianjin, 300050, China
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Wuhan, 430022, China
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Wuxi, 214023, China
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Xiamen, 361004, China
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Xuzhou, 221000, China
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Xuzhou, 221009, China
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Yangzhou, 225001, China
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Yinchuan, 750004, China
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Zhanjiang, 524004, China
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Zunyi, 563100, China
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Barranquilla, 80007, Colombia
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Ibagué, 730006, Colombia
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Rionegro, 054047, Colombia
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Zipaquirá, 200251, Colombia
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Brest, 29609, France
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Dijon, 21079, France
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Grenoble, 38043, France
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Lyon, 69317, France
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Marseille, 13915, France
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Montivilliers, 76290, France
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Montpellier, 34090, France
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Pessac, 33604, France
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Saint-Herblain, 44093, France
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Toulouse, 31059, France
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Ahrensburg, 22926, Germany
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Bamberg, 96049, Germany
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Berlin, 10717, Germany
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Berlin, 12157, Germany
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Cologne, 51069, Germany
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Darmstadt, 64283, Germany
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Halle, 6108, Germany
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Marburg, 35037, Germany
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München, 80336, Germany
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München-Pasing, 81241, Germany
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Peine, 31224, Germany
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Alexandroupoli, 68100, Greece
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Athens, 11527, Greece
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Exohi Thessaloniki, 57010, Greece
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Ioannina, 45500, Greece
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Pátrai, 26500, Greece
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Thessaloniki, 57010, Greece
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Ashkelon, 78278, Israel
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Beersheba, 8410101, Israel
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Jerusalem, 9372212, Israel
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Kfar Saba, 4428164, Israel
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Rehovot, 76100, Israel
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Tel Aviv, 6423906, Israel
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Bari, 70124, Italy
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Massa, 54100, Italy
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Milan, 20142, Italy
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Milan, 20157, Italy
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Naples, 80131, Italy
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Roma, 00168, Italy
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Salerno, 84131, Italy
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San Donà di Piave, 30027, Italy
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Sassari, 07100, Italy
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Statte, 74010, Italy
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Telese Terme, 82037, Italy
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Tradate, 21049, Italy
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Vercelli, 13100, Italy
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Verona, 37134, Italy
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Lima, 15036, Peru
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Lima, 15046, Peru
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Lima, 15088, Peru
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Lima, LIMA 21, Peru
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Baguio City, 2600, Philippines
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Cebu City, 6000, Philippines
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Iloilo City, 5000, Philippines
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Bialystok, 15-044, Poland
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Bialystok, 15-704, Poland
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Bychawa, 23100, Poland
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Bydgoszcz, 85-796, Poland
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Katowice, 40-648, Poland
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Krakow, 30-033, Poland
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Lublin, 20-412, Poland
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Ostrowiec Świętokrzyski, 27-400, Poland
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Ostróda, 14-100, Poland
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Poznan, 60-693, Poland
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Poznan, 61-578, Poland
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Rzeszów, 35-205, Poland
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Skierniewice, 96-100, Poland
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Sosnowiec, 41-208, Poland
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Wroclaw, 53-301, Poland
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Ponce, 00717, Puerto Rico
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Brasov, 500283, Romania
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Bucharest, 050159, Romania
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Cluj-Napoca, 400371, Romania
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Constanța, 900002, Romania
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Timișoara, 300002, Romania
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Penza, 440067, Russia
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Saratov, 410012, Russia
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Hsinchu, 300, Taiwan
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Kaohsiung City, 807, Taiwan
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Kaohsiung City, 82445, Taiwan
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Taichung, 40443, Taiwan
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Taichung, 40705, Taiwan
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Taipei, 100, Taiwan
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Taipei, 110, Taiwan
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Taoyuan District, 333, Taiwan
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Yunlin, 640, Taiwan
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Bang Kra So, 11000, Thailand
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Bangkok, 10700, Thailand
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Hat Yai, 90110, Thailand
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Khon Kaen, 40002, Thailand
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Muang,, 55000, Thailand
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Muang, 22000, Thailand
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Mueang, 20000, Thailand
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Nakhon Ratchasima, 30000, Thailand
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Bradford, BD9 6RJ, United Kingdom
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Corby, NN17 2UR, United Kingdom
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Corby, NN18 9EZ, United Kingdom
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Enfield, EN3 4GS, United Kingdom
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Hampshire, SO16 6YD, United Kingdom
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High Wycombe, HP11 2QW, United Kingdom
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Northwood, HA6 2RN, United Kingdom
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Preston, PR2 9QB, United Kingdom
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Shipley, BD18 3SA, United Kingdom

Conditions

Explore the condition pages connected to this study.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)