New device may ease COPD breathlessness after exercise

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \> 18 years; * COPD stage GOLD II to IV; * Had completed a pulmonary rehabilitation programme at the investigational site; * 6-minute walk test \< 350 meters before and/or after completing the pulmonary; rehabilitation program; * mMRC dyspnea scale ≥ 2; * Pulmonary hyperinflation (ratio between residual volume to total lung capacity superior to 50%, and either total lung capacity superior to 130% or functional residual capacity superior to 130%); * With or without oxygen supplementation; * Stable condition (no exacerbation or change in treatment in the last 4 weeks); * Naïve to intermittent intrapulmonary deflation. * Regulatory criteria (social security affiliation; adult patient who has read and understood the information letter and signed the informed consent form). Non-inclusion Criteria: * Pregnant women or likely to be; * Patients under guardianship or curatorship; * Inability to consent; * Primary diagnosis of another chronic obstructive respiratory disease such as asthma or primary bronchiectasis; * Orthopedic, neurological, vascular, or neuromuscular conditions that limit walking or require walking aids; * Severe or unstable cardiovascular disease (uncontrolled cardiac arrhythmias, severe heart failure, recent myocardial infarction, unstable angina); * Patients actively requiring assistance with inspiration (e.g. ventilatory assistance with endotracheal tube, tracheostomy tube, or ventilated with a mask; patients with neuromuscular disease with respiratory muscle weakness; patients with inability to cough forcefully and independently); * Hemodynamic instability; * Recent pneumothorax (within the last 3 months); * Recent pulmonary or upper airway surgery (within the last month); * Referral to a pulmonary rehabilitation program in preparation for thoracic surgery (lung volume reduction, lung transplantation, or lung resection for non-small cell lung cancer); * Use of an electrical mechanical device for airway clearance during the study period (in-exsufflator, high-frequency chest oscillation, etc.); * Active cancer; * Severe episode of hemoptysis in the last 3 months; * Severe tracheomalacia. Exclusion Criteria: * Withdrawal of consent; * Acute COPD exacerbation between visits or onset of cardiorespiratory instability; * Use of an electrical mechanical device for airway clearance during the study period (in-exsufflator, high-frequency chest oscillation, etc.).