Chilling after heart stopping: could cooling save more brains?

NCT ID NCT07086703

First seen Oct 31, 2025 · Last updated May 06, 2026 · Updated 26 times

Summary

This study looks at whether lowering body temperature to 33°C (hypothermia) after a cardiac arrest that happens in the hospital helps more people survive with good brain function compared to keeping them at a normal temperature. About 788 adults who are unconscious after being revived will be randomly assigned to one of two temperature management strategies. The goal is to see if cooling leads to better outcomes six months later.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHM - Hôpital Nord

    Marseille, 13015, France

    Contact

  • APHP - Hôpital Ambroise Paré

    Paris, 92200, France

    Contact

  • APHP- Hôpital Cochin

    Paris, 75679 cedex 14, France

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  • APHP-Hôpital Saint-Antoine

    Paris, 75517, France

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  • CH Brocéliande Atlantique

    Vannes, 56017 cedex 1, France

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  • CH Dubois Brive

    Brive-la-Gaillarde, 19312 cedex, France

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  • CH Public du Cotentin

    Cherbourg, 50102, France

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  • CH d'Angoulême

    Angoulême, 16000, France

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  • CH de Roanne

    Roanne, France

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  • CH de Rodez

    Rodez, 12027, France

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  • CHD Vendée

    La Roche-sur-Yon, 85025 Cedex, France

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  • CHR d'Orléans

    Orléans, 45100, France

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  • CHRU de Strasbourg

    Strasbourg, 67091 cedex, France

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  • CHRU de Tours

    Tours, 37044 Cedex 9, France

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  • CHRU- Hôpital Roger Salengro

    Lille, 59307 cedex, France

  • CHU Bocage

    Dijon, 77908, France

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  • CHU Charleroi

    Charleroi, Belgium

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  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003 cedex 1, France

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  • CHU Dupuytren

    Limoges, 87042 Cedex 1, France

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  • CHU Les Abymes

    Pointe-à-Pitre, La Guadeloupe, 97110, Guadeloupe

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  • CHU de Caen

    Caen, 14033, France

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  • CHU de Nantes

    Nantes, France

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  • Clinique Saint-PIerre

    Ottignies, Belgium

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  • Hôpital André Mignot

    Le Chesnay, 78150, France

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  • Hôpital Edouard Herriot

    Lyon, 69437, France

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  • Hôpital Erasme

    Brussels, Belgium

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  • Hôpital Privé Jacques Cartier

    Massy, 91300, France

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  • Hôpital Sainte-Musse

    Toulon, 83100, France

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  • Hôpital Simone Veil

    Cannes, 06414 cedex, France

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  • Hôpital Universitaire de Bruxelles

    Jette, Belgium

    Contact

  • Hôpital Universitaire de Gand

    Ghent, Belgium

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  • Hôpital de l'Archet

    Nice, 06200, France

    Contact

Conditions

Explore the condition pages connected to this study.