New drug cocktail aims to fight stomach cancer in the abdomen
NCT ID NCT05802056
First seen Jun 25, 2026 · Last updated Jul 02, 2026 · Updated 5 times
Summary
This early-phase trial tests whether adding an immune-boosting drug (aldesleukin) to standard chemotherapy and another immunotherapy (nivolumab) can help control stomach cancer that has spread to the lining of the abdomen. About 15 adults with this advanced cancer will receive the combination. The main goals are to check safety and see if the cancer shrinks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nivolumab and aldesleukin (a lab-made immune protein)
- What this could lead to
- If this works, it could point toward a new treatment option for stomach cancer that has spread to the abdomen lining.
- What could go wrong
- This is a very early, small phase 1 trial with only 15 people. It is designed mainly to check safety, not yet to prove if the combination works. Side effects from the immune-boosting drugs can be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new drug combo shrink Hard-to-Treat tumors?
- Can an immunotherapy combo shrink stomach tumors before surgery?
- Can adding immunotherapy to chemotherapy improve gastric cancer outcomes?
- Can immunotherapy outperform chemo after stomach cancer surgery?
- Can a smart drug home in on Hard-to-Treat cancers?