Blood and spinal fluid samples could unlock better tests for rare neurological diseases

NCT ID NCT05370079

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study collects blood and optional spinal fluid samples from 350 people with Parkinson's, ALS, glioblastoma, certain cancers, or rheumatoid arthritis. The goal is to find new genetic markers that could lead to better diagnostic tests for autoimmune encephalitis and paraneoplastic neurological syndromes, which are rare and hard to diagnose. Participants provide samples once, and no treatment is given.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to more accurate diagnostic tests for rare neurological conditions like autoimmune encephalitis.

What could go wrong

This is an observational sample-collection study, not a treatment trial. It may not directly benefit participants and results may take years to apply.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis cancer glioblastoma Parkinson disease rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospices Civils de Lyon

    RECRUITING

    Bron, 69500, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••